Development of a method for extraction and determination of 4,4′-methylenedianiline in soils by solid-phase extraction and UPLC-MS-MS

Brunet, Camille; Aubin, Simon; Gagné, Sébastien; West, Robert J.; Lesage, Jacques

doi:10.1080/10826076.2018.1539673

Cited by 3 publications

(3 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this work, care was also taken to use sampling and analysis methods that did not cause decomposition of the polymer matrix ( Brunet et al, 2018 ; Donchenko et al, 2020 ; Johnson et al, 2010 ). Two consecutive extractions were used, as was done by Hillier et al (2001) .…”

Section: Discussionmentioning

confidence: 99%

“…The migration testing method used was designed to maintain the integrity of the PU polymer matrix by using an acidic aqueous extraction solution in lieu of solvents (see Introduction and Brunet et al, 2018 , e.g.).…”

Section: Discussionmentioning

confidence: 99%

“…Methods can also be prone to interference between diisocyanates and diamines if these are present simultaneously and immediate derivatization of the isocyanates to avoid hydrolysis is not ensured ( HSE, 2014 ). Recently, analysis methods have been developed that have minimal effects on the PU polymer matrix and/or enable the simultaneous detection of diisocyanates and diamines in the same sample by including an isocyanate derivatizing agent in the acidic solution that is used for extraction of the diamines ( Brunet et al, 2018 ; Donchenko et al, 2020 ; Johnson et al, 2010 ; Karlsson, 2023 ). For these reasons, this work employed very similar methods for the extraction, emission, and migration studies undertaken.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Emission and time-resolved migration rates of aromatic diamines from two flexible polyurethane foams

Karlsson¹,

Spence²,

Plehiers³

2023

Toxicol Ind Health

View full text Add to dashboard Cite

Performing risk assessments (RA) on household use of flexible polyurethane (PU) foams requires access to reliable data about emission and migration of potential diamine impurities. A toluene diisocyanate (TDI) and a methylene diphenyl diisocyanate (MDI) based foam were thermally treated to enable measurements on samples with defined concentrations of the corresponding diamines, toluene diamine (TDA), and methylene dianiline (MDA). The thermally treated foams used for emission testing contained up to 15 mg.kg−1 of TDA and 27 mg.kg−1 of MDA. Those used for migration testing contained 5.1 mg.kg−1 of TDA and 14.1 mg.kg−1 of MDA. Stability of the thermally generated diamines was sufficient for testing over a 37-day period. Analytical techniques that did not decompose the polymer matrix were applied. Emission rates for TDA and MDA isomers were less than the limit of quantitation (LOQ) of 0.008–0.07 μg.m−2.h−1. Migration was studied using samples of the same thermally treated foams over a 35-day period. Quantifiable migration of MDA from the MDI-based foam was only observed on Days 1 and 2. From Day 3 onward, migration rates were less than the LOQ. Quantifiable migration of TDA from the TDI-based foam rapidly decreased with time and was only observed on Days 1 thru 3. From Day 4 onward, migration rates were less than the LOQ. Theoretically, the migration rate should be inversely proportional to the square root of time (t) as t−0.5. This relationship was confirmed by the experimental data and enables extrapolating migration values to more extended time periods to conduct RAs.

show abstract