Development of a molecularly imprinted polymer for prometryne clean-up in the environment

Abstract

Molecularly imprinted polymers (MIPs) are prepared on the surface of modified silica gel using prometryne as a template, methacrylic acid as the functional monomer, ethylene glycol dimethacrylate as a crosslinker, and 2,2-azobisisobutyronitrile as an initiator. The structure of the MIPs was characterized using SEM and FTIR spectroscopy. The selectivity of the MIPs for the template molecule prometryne was proven by adsorption experiments. Highly selective SPE cartridges of MIP particles were developed and an optimized prometryne procedure was developed for the enrichment and clean-up of prometryne residues in water, soil, and wheat samples. The concentrations of prometryne in the samples were analyzed by HPLC. The average recoveries of prometryne spiked for water at 0.05∼0.8 mg/L were 101.47-106.65% and the RSD was 2.63-4.71%. The average recoveries of prometryne spiked for soil at 0.05∼0.8 mg/L were 87.34-94.91% with the RSD being 2.77-8.41%. The average recoveries of prometryne spiked for wheat plant at 0.2∼2.0 mg/kg were 91.04-97.76% with the RSD being 6.53-10.69%. The method developed here can be regenerated and repeatedly used more than two dozen times.

On‐line solid‐phase extraction for liquid chromatography–mass spectrometry analysis of pesticides

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Molecularly imprinted polymer functionalized magnetic Fe3O4 for the highly selective extraction of triclosan

“…At present, polymeric or silica‐based sorbents and carbon nanomaterials are usually applied in this step, but some of them lack selectivity especially in complex matrices, which results in the co‐extraction of target analytes and interfering substances. In the recent years, the application of SPE procedures involving the use of synthetic antibody mimics, such as molecularly imprinted polymers (MIPs), has received more and more attentions as an attractive alternative for the analysis of complex samples .…”

Determination of macrolide antibiotics residues in pork using molecularly imprinted dispersive solid‐phase extraction coupled with LC–MS/MS

“…By virtue of their robustness, reliability, and resistance to harsh conditions (high temperatures, corrosive chemical media, extreme pH values, etc. ), MIPs have been widely used in purifying and separating traditional Chinese medicines , identifying chiral drugs , monitoring environmental pollutants , accelerating chemical catalysis , and synthesizing biomimetic sensors . During synthesis, the interactions between the binding sites of the template and those of the functional monomer play a key role in the specific recognition ability of MIPs.…”