Development of a Neurobehavioral Battery for Children Exposed to Neurotoxic Chemicals

Rohlman, Diane S.; Anger, W. Kent; Tamulinas, Alys; Phillips, Jacki; Bailey, Steffani R.; McCauley, Linda

doi:10.1016/s0161-813x(01)00049-3

Cited by 33 publications

(24 citation statements)

References 30 publications

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“…Aside from the PENTB which was specifically developed to assess children, most research directed toward testing children has involved adaptations of neurobehavioral test batteries originally designed to test adults (Dahl, et al, 1996;Rohlman, et al, 2001b) or tasks developed in the animal laboratory (Paule, et al, 1999). Tests that have detected neurotoxic effects in adults are appealing choices for similar studies in children because they have a proven ability to detect chemical exposure effects.…”

Section: Neurobehavioral Assessment Of Childrenmentioning

confidence: 99%

“…Computer-based tests may easily be adapted for use with children. Some of the modifications to parameters for computerbased tests used with adults include: (1) shortening the test duration; (2) increasing the stimulus display time and inter-stimulus interval; (3) changing the stimuli used from letters to animal shapes; (4) changing the presentation format from visual to auditory; and (5) using additional reinforcement during the test session (Dahl, et al, 1996;Rohlman, et al, 2001b). These changes help to maintain the child's motivation during the test session.…”

Section: Neurobehavioral Assessment Of Childrenmentioning

confidence: 99%

“…Although many tests do not require language for the child's performance on the tests, the instructions need to be adequately translated. Cultural variation also needs to be taken into account when translating tests into another language Puente and Ardila, 2000;Rohlman, et al, 2001b). Stimuli or items used in tests may have more than one correct translation, especially when different local dialects are taken into account.…”

Section: Cross-cultural Developmentmentioning

confidence: 99%

“…The battery was assembled by combining computerized tests from the BARS, tests adapted from the PENTB, and a test of recall and recognition, the Object Memory test (Mahurin, et al, 1992). The neurobehavioral tests and functions assessed are shown in Table 1. A multi-step process was used to develop the current test battery to assess neurobehavioral performance in preschool children (Rohlman, et al, 2000b;Rohlman, et al, 2001b). Parameter settings for the computer-based tests (e.g., number of trials, difficulty level) that would be appropriate for young children were initially assessed in English-speaking preschool children (Rohlman, et al, 2000b).…”

Section: Development Of the Current Batterymentioning

confidence: 99%

“…The test battery in its present form has been standardized in a sample that included both English and Spanish speaking 4-to 6-year olds (Rohlman, et al, 2000b;Rohlman, et al, 2001b). The battery is individually administered, with instructions relying on demonstration and practice trials.…”

Section: Neurobehavioral Test Batterymentioning

confidence: 99%

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Adaptation of the Behavioral Assessment and Research System (BARS) for evaluating neurobehavioral performance in Filipino children

et al. 2008

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Neurobehavioral tests have long been used to assess health effects in exposed working adult populations. The heightened concern over the potential impact of environmental exposures on neurological functioning in children has led to the development of test batteries for use with children. There is a need for reliable, easy-to-administer batteries to assess neurotoxic exposure in children. One such test battery previously validated with Spanish-and English-speaking children ages 4 and older, combines computerized tests from the Behavioral Assessment and Research System (BARS) with non-computerized tests. The goal of the present study was to determine the feasibility of using standardized neurobehavioral tests in preschool and school-aged Filipino children. Test instructions were translated into the vernacular, Tagalog or Tagalog-English ("Taglish") and some instructions and materials were modified to be appropriate for the target populations. The battery was administered to 4 to 6 year old Filipino children (N=50). The performance of the Filipino children was compared to data previously collected from Spanish-and English-speaking children tested in the US. The majority of children had no difficulty completing the tests in the battery with the exception of the Symbol-Digit test and Digit Span-reverse. The three groups showed similar patterns of performance on the tests and the older children performed better than the younger children on all of the tests. The findings from this study demonstrate the utility of using this test battery to assess cognitive and motor performance in Filipino children. Tests in the battery assess a range of functions and the measures are sensitive to age differences. The current battery has been utilized in several cultures and socio-economic status classes, with only minor modifications needed. This study demonstrates the importance of pilot testing the methods before use in a new population, to ensure that the test is valid for that culture.

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Section: Neurobehavioral Assessment Of Childrenmentioning

confidence: 99%

Section: Neurobehavioral Assessment Of Childrenmentioning

confidence: 99%

Section: Cross-cultural Developmentmentioning

confidence: 99%

Section: Development Of the Current Batterymentioning

confidence: 99%

Section: Neurobehavioral Test Batterymentioning

confidence: 99%

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Adaptation of the Behavioral Assessment and Research System (BARS) for evaluating neurobehavioral performance in Filipino children

et al. 2008

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Neurotoxicology and Behavior

Boyes

2023

Patty's Toxicology

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Neurotoxicity is important to consider as a component of occupational and environmental safety and health programs. The failure to do so has contributed to a number of tragic cases in which people were irreparably harmed by exposure to compounds that proved toxic to the nervous system. The field of neurotoxicology originated in response to several episodes of mass poisoning and developed through advances in clinical practice, scientific research, and regulatory actions. This chapter reviews broadly the development of the field of neurotoxicity and discusses some of the predominant current issues. The chapter includes consideration of the features of the nervous system that make it susceptible to toxicity, the response to injury, the evaluation of sensory, cognitive, and motor functions, and effects on emotionality, mood, and social conduct. An emphasis is placed on functional outcomes that may be especially important in occupational and industrial hygiene settings. There is increasingly an emphasis on potential toxic effects on neurodevelopment and contributions to neurodegenerative diseases. Also, there is a large and growing effort to develop more rapid and cost‐efficient screening tests for potential neurotoxicity. A brief overview of some of the major classes of neurotoxic substances is provided including metals, solvents, pesticides, persistent organic compounds, and air pollution. Finally, the need for programs to prevent neurotoxic illness is discussed.

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Neurotoxicology and Behavior

Boyes¹

2012

Patty's Toxicology

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Neurotoxicity is important to consider as a component of occupational and environmental safety and health programs. The failure to do so has contributed to a number of cases in which workers, consumers of manufactured products, and people exposed in the environment were irreparably harmed by exposure to compounds that proved toxic to the nervous system. The field of neurotoxicology originated in response to several episodes of mass poisoning and developed through advances in clinical practice, scientific research, and regulatory actions. This chapter reviews broadly the development of the field of neurotoxicity and discusses some of the predominant current issues. The chapter includes an introduction to the structure and function of the nervous system, the response to injury, the evaluation of sensory, cognitive, and motor functions, and effects on emotionality, mood, and social conduct. Recently, there has been a growing emphasis on potential toxic effects on neurodevelopment and contributions to neurodegenerative diseases. Also, there is a large and growing effort to develop more rapid and cost‐efficient screening tests for potential neurotoxicity. A brief overview of some of the major classes of neurotoxic substances is provided including metals, solvents, pesticides, and persistent organic compounds. Finally, the need for programs to prevent neurotoxic illness is discussed.

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Development of a Neurobehavioral Battery for Children Exposed to Neurotoxic Chemicals

Cited by 33 publications

References 30 publications

Adaptation of the Behavioral Assessment and Research System (BARS) for evaluating neurobehavioral performance in Filipino children

Adaptation of the Behavioral Assessment and Research System (BARS) for evaluating neurobehavioral performance in Filipino children

Neurotoxicology and Behavior

Neurotoxicology and Behavior

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