Development of a new consumable-free thermal modulator for comprehensive two-dimensional gas chromatography

Panić, Ognjen; Górecki, Tadeusz; McNeish, Christopher; Goldstein, Allen H.; Williams, Brent J.; Worton, David R.; Hering, Susanne V.; Kreisberg, N. M.

doi:10.1016/j.chroma.2011.03.024

Cited by 35 publications

(22 citation statements)

References 22 publications

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“…The most commonly used modulators in atmospheric chemistry have been cryogenic and valvebased modulators (Hamilton 2010). However, because robustness, simplicity, and low operating costs are attractive features, recent work has focused on the development of improved versions of this type of modulator (Libardoni et al 2005(Libardoni et al , 2006(Libardoni et al , 2010Panić et al 2011). Successful single-stage modulation has been reported using recirculated cold air (−30…”

Section: Requirements For the Ideal Modulator For In-situ Measurementsmentioning

confidence: 99%

“…• C. This thermal limit led to longer analysis times (greater than four hours to elute tetracontane, C 40 H 82 ) and significant band broadening in both dimensions as a result of an extended isothermal period at the end of each run (Panić et al 2011). The isothermal period at 280…”

Section: Chromatographic Column Selectionmentioning

confidence: 99%

“…The modulator employed in our 2D-TAG system has been specifically tailored for field analysis of semi-and non-volatile organics in atmospheric aerosols, where mechanical robustness and minimal consumables are an important design constraint. The modulator employed here, a simplified version of the modulator described by Panić et al (2011), is a thermal modulator most closely related to the early work of Liu and Phillips (1991). The modulator consists of a short (15 cm) segment of flattened, 0.53 mm OD × 0.28 mm ID, deactivated Silcosteel TM tubing continuously cooled by forced air convection and heated by 100-ms-duration capacitive electric discharge pulse.…”

Section: Single-stage Modulationmentioning

confidence: 99%

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Thermal Desorption Comprehensive Two-Dimensional Gas Chromatography: An Improved Instrument for In-Situ Speciated Measurements of Organic Aerosols

Worton

Kreisberg

Isaacman-VanWertz

et al. 2012

Aerosol Science and Technology

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The organic fraction is a major constituent of fine atmospheric particulate matter, though its chemical composition is complex and not well understood. This complexity presents an extreme analytical challenge and is well suited to analysis by comprehensive twodimensional gas chromatography (GC × GC). This has recently been coupled to a thermal desorption aerosol gas (TAG) chromatograph instrument to provide improved in-situ, hourly measurement of speciated organic compounds in atmospheric aerosols (2D-TAG). The original 2D-TAG instrument utilized a flame ionization detector, dual-stage modulator, and a second-dimension column that proved to be thermally unstable under optimal analysis conditions, which limited compound identification, instrument robustness, and time resolution. In this paper, we address these shortcomings by demonstrating the successful integration of a time-of-flight mass spectrometer (TOFMS), development of a simplified hybrid thermo-pneumatic modulator, and incorporation of a more thermally stable secondary column. These improvements resulted in an instrument capable of providing detailed speciated information of organic tracer compounds in atmospheric aerosols in near real time.

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Section: Requirements For the Ideal Modulator For In-situ Measurementsmentioning

confidence: 99%

Section: Chromatographic Column Selectionmentioning

confidence: 99%

Section: Single-stage Modulationmentioning

confidence: 99%

See 1 more Smart Citation

Thermal Desorption Comprehensive Two-Dimensional Gas Chromatography: An Improved Instrument for In-Situ Speciated Measurements of Organic Aerosols

Worton

Kreisberg

Isaacman-VanWertz

et al. 2012

Aerosol Science and Technology

Self Cite

View full text Add to dashboard Cite

show abstract

“…(Panic et al, 2011), and improvement of data handling and evaluation (Wang et al, 2010;Kim et al, 2011;Koek et al, 2011) should be mentioned.…”

Section: Application Of Gc × Gc and Its Current Trendsmentioning

confidence: 99%

Comprehensive Two-Dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry in Human Metabolomics

Wojtowicz¹,

Zrostlı́ková²,

Šťastná³

et al. 2012

Gas Chromatography - Biochemicals, Narcotics and Essential Oils

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“…In 2011, Panic et al (Panic et al, 2011) developed a new consumable-free thermal modulator for GC×GC. The modulator was constructed from a trapping capillary, installed outside the GC oven, and coated inside with PDMS stationary phase.…”

Section: Gcgc Instrumentation and Optimization Of Operating Conditionsmentioning

confidence: 99%

Recent Applications of Comprehensive Two-Dimensional Gas Chromatography to Environmental Matrices

Cardinaël¹,

Auguste²,

Peulon-Agasse³

2012

Advanced Gas Chromatography - Progress in Agricultural, Biomedical and Industrial Applications

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Development of a new consumable-free thermal modulator for comprehensive two-dimensional gas chromatography

Cited by 35 publications

References 22 publications

Thermal Desorption Comprehensive Two-Dimensional Gas Chromatography: An Improved Instrument for In-Situ Speciated Measurements of Organic Aerosols

Thermal Desorption Comprehensive Two-Dimensional Gas Chromatography: An Improved Instrument for In-Situ Speciated Measurements of Organic Aerosols

Comprehensive Two-Dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry in Human Metabolomics

Recent Applications of Comprehensive Two-Dimensional Gas Chromatography to Environmental Matrices

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