Development of a New Micromixer “Elis” for Fluid Mixing and Organic Reactions in Millidevices

Santana, Harrson Silva; Silva, João L.; Silva, Adriano G. P. da; Rodrigues, Alan; Amaral, Ronaldo; Noriler, Dirceu; Taranto, Osvaldir Pereira

doi:10.1021/acs.iecr.1c00770

Cited by 25 publications

(7 citation statements)

References 52 publications

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“…In recent years, micromixer has been developing rapidly and widely used in many disciplines, e.g., biology, − chemistry, − energy industry, , and medicine, − for chemical detection and analysis. Conventionally, the dimensions of the micromixer are below the submillimeter, and the characteristic velocity of the fluid is on the orders of millimeters per second or smaller.…”

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confidence: 99%

Mixing and Flow Transition in an Optimized Electrokinetic Turbulent Micromixer

et al. 2022

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Micromixer is a key element in a lab on a chip for broad applications in the analysis and measurement of chemistry and engineering. Previous investigations reported that electrokinetic (EK) turbulence could be realized in a "Y" type micromixer with a cross-sectional dimension of 100 μm order. Although the ultrafast turbulent mixing can be generated at a bulk flow Reynolds number on the order of unity, the micromixer has not been optimized. In this investigation, we systematically investigated the influence of electric field intensity, AC frequency, electric conductivity ratio, and channel width at the entrance on the mixing effect and transition electric Rayleigh number in the "Y" type electrokinetic turbulent micromixer. It is found that the optimal mixing is realized in a 350 μm wide micromixer, under 100 kHz and 1.14 × 10 5 V/m AC electric field, with an electric conductivity ratio of 1:3000. Under these conditions, a degree of mixedness of 0.93 can be achieved at 84 μm from the entrance and 100 ms. A further investigation of the critical electric field and the critical electric Rayleigh number indicates that the most unstable condition of EK flow instability is inconsistent with that of the optimal mixing in EK turbulence. To predict the evolution of EK flow under high Ra σ and guide the design of EK turbulent micromixers, it is necessary to apply a computational turbulence model instead of linear instability analysis.

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confidence: 99%

Mixing and Flow Transition in an Optimized Electrokinetic Turbulent Micromixer

et al. 2022

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“…Most mixing operations in passive micromixers are heavily influenced by microchannel geometry and fluid flow characteristics. ,, Numerous microchannel structure schemes have been proposed to enhance fluid mixing in passive micromixers, including channel intersecting, converging, curving, and convergence–divergence, as well as channel injection, stratification, hydrodynamic focusing, and cross-flow impact approaches . Among these, the planar passive curved microchannel mixers have been widely developed due to their high mixing efficiency and straightforward fabrication processes .…”

Section: Introductionmentioning

confidence: 99%

Multidirectional Vortex Micromixer Utilizing a Curved Channel with Variable Cross-Sectional Circular Arc Mixing Chambers

Xue,

Jin

2024

Ind. Eng. Chem. Res.

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A planar passive multidirectional vortex micromixer with a simple geometry and easy fabrication has been proposed and developed. The design of the microchannel structure integrates the flow impact, Dean flow, and vortex mixing effect by periodically arranging jet channels and variable cross-sectional circular arc mixing chambers. The complex vortex flow facilitates the breaking of the original laminar barrier of the fluid, which leads to efficient mixing by increasing the contact area of fluid mediums and reducing the diffusion distance of fluid molecules. The micromixer has been fabricated using precision micromilling technology, and the fluid mixing process was observed using a microscope imaging system. The fluid mixing process was simulated using commercial software, and the obtained numerical simulation results are consistent with the experimental results. At a flow Reynolds number of 70, the mixing index of the micromixer with a radius ratio of 2.66 is about 72% at the end of the first mixing module, and after completion of the flow of three mixing modules, the mixing index of its outlet channel cross section can reach more than 95%. This micromixer's simple and reliable performance makes it ideal for flexible applications in micro total analysis systems.

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“…The strategies for introducing chaotic flows into the mixer channel may be divided into three categories according to the shapes of the mixing channel. The simplest design utilizes a two- or three-dimensional structure inside the channel with repeated units to divide, stretch, twist, or fold the original parallel flow. − The second method is to add obstacles of various shapes in the channel to redirect the flow and redistribute the fluid. − The third one is to add attachments onto the inner wall of the channel to generate transverse and rotational flows . Stroock et al proposed a staggered herringbone structure arranged at the bottom of the microchannel, which ingeniously generates transverse flows due to the resistance from multiple directions.…”

Section: Introductionmentioning

confidence: 99%

Mixing Enhancement in a Chaotic Micromixer with Reversed Ridges and Grooves

Chen,

Lin,

Pan

et al. 2023

Ind. Eng. Chem. Res.

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A novel micromixer named reversed ridges and grooves micromixer (RRGM) with chaotic and passive characteristics is devised and analyzed numerically. Compared with a slanted grooves micromixer (SGM), a barrier-embedded micromixer (BEM), and a circulation-disturbance micromixer (CDM), the RRGM achieves an excellent mixing performance for Reynolds number (Re) in a range of 0.01 ≤ Re ≤ 100, especially at Re ≤ 10. The mixing index is adopted as the objective function to evaluate the mixing performance. The Lagrangian particle tracking method is employed to further observe the chaotic behavior in the mixing process and to explain the mechanism of chaotic mixing. The combination of ridges and grooves actively accelerates the stretching and folding of fluids, forming a pair of continuously changing asymmetrical hyperbolic vortices along the entire mixing channel. Three design parameters related to the performance, namely, slanted angle of ridges, slanted angle of grooves, and height of groove and ridge, are explored to optimize the mixing performance. The slanted angle of 45°is ascertained as the optimal value for both the ridges and grooves. At Re ≤ 1, the height of ridges and grooves of 30 μm is the best choice, whereas at Re ≥ 10, a higher mixing index is obtained by increasing the height of grooves and ridges, which is attributed to a greater flow disturbance from the inertial dominance.

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Development of a New Micromixer “Elis” for Fluid Mixing and Organic Reactions in Millidevices

Cited by 25 publications

References 52 publications

Mixing and Flow Transition in an Optimized Electrokinetic Turbulent Micromixer

Mixing and Flow Transition in an Optimized Electrokinetic Turbulent Micromixer

Multidirectional Vortex Micromixer Utilizing a Curved Channel with Variable Cross-Sectional Circular Arc Mixing Chambers

Mixing Enhancement in a Chaotic Micromixer with Reversed Ridges and Grooves

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