The word autopsy is formed from two Greek words, Autos and Optos. The meaning of the word Autos is self and the word Optos is seen. Thus, autopsy means seeing of self. An autopsy is of two types. Medicolegal Autopsy and Histopathological or Clinical Autopsy. In this chapter, we mainly focus on the Medicolegal autopsy, what is the aim of the autopsy. What are the prerequisites of the autopsy? Where medicolegal autopsy can be carried out? Who can carry out the autopsy. What are the different incisions of doing a medico-legal autopsy? We also discuss which viscera are to persevere in different autopsy procedures and which trace elements are to be collected in common medicolegal autopsies. How viscera and trace evidence collected from the dead body are preserved. We will also discuss, in brief, the preservatives used.