Development of a new synthetic xerogel nanoparticles of silver and zinc oxide against causative agents of dermatophytoses

AL-Janabi, Ali Abdul Hussein S.; Bashi, Abass M.

doi:10.1080/09546634.2018.1506079

Cited by 7 publications

(4 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…14 Dermatophytoses: Al Janabi et al observed xerogel nanoparticles composed of ZnO had antidermatophytic action in specific concentrations. 15 In the study, 30 patients with tinea corporis received topical 10% zinc sulfate solution twice daily for two months, complete cure response was observed in 13 (43.33%) patients, partial response in 7 (23.34%) patients and no response in 10 (33.33%) patients while in placebo group the clinical response was two (6.67 %) patients with partial improvement and 28 (93.33%) patients with no improvement. 16 Bromhidrosis: Foot odor is a common sociomedical problem that affects the feet of human beings of different etiological factors.…”

Section: Zinc As a Therapymentioning

confidence: 97%

Zinc Therapy in Dermatology: A Review and Update

Aryal

Bhattarai

2021

Nepal J Dermatol Venereol & Leprol

View full text Add to dashboard Cite

Zinc is a micronutrient used over the years for many dermatological conditions such as infections, inflammatory dermatoses, pigmentary disorders, neoplasias etc. It is used in both elemental as well as salt form, either in topical or in oral form as a therapy. An average adult weighing 70 kg has a body zinc content of 1.4–2.3 gm. The role of zinc in deficiency disorder like acrodermatitis enteropathica is already established and used widely as treatment. Zinc has been identified as effective in the treatment of various disorders but it cannot be used as the replacement for proven first line treatment. Zinc can be used as adjuvant therapy in many dermatological disorders. This is a narrative review where various use of zinc as therapy in dermatological disorders is highlighted.

show abstract

Section: Zinc As a Therapymentioning

confidence: 97%

Zinc Therapy in Dermatology: A Review and Update

Aryal

Bhattarai

2021

Nepal J Dermatol Venereol & Leprol

View full text Add to dashboard Cite

show abstract

“…246 Xerogel formed of Ag NPs and ZnO NPs exhibited satisfactory susceptibility against Trichophyton mentagrophytes and Trichophyton verrucosum, dermatophyte fungi that often cause a superficial skin disease called dermatophytosis. 247 ZnO NP− lignin aggregates showed significant antifungal activity against selected fungal strains like Aspergillus fumigatus, Aspergillus penicilloides, C. albicans, Conidiobolus coronatus, and Microsporum cookei. 248 The 40 nm ZnO NPs synthesized by a conventional chemical procedure demonstrated antifungal action on strains of Aspergillus niger and Botrytis cinerea, being more efficient in inactivating B. cinerea.…”

Section: Antibacterial Applicationsmentioning

confidence: 99%

“…In this context, Alhazmi and colleagues proved that 25 nm ZnO NPs synthesized by precipitation method showed an impactful antifungal effect against isolates of azole-resistant Aspergillus flavus . Xerogel formed of Ag NPs and ZnO NPs exhibited satisfactory susceptibility against Trichophyton mentagrophytes and Trichophyton verrucosum, dermatophyte fungi that often cause a superficial skin disease called dermatophytosis . ZnO NP–lignin aggregates showed significant antifungal activity against selected fungal strains like Aspergillus fumigatus, Aspergillus penicilloides, C.…”

Section: Antimicrobial Applicationsmentioning

confidence: 99%

Synthesis and Antimicrobial Applications of ZnO Nanostructures: A Review

Izzi

Sportelli

Torsi

et al. 2023

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

ZnO nanostructures (ZnO NSs) are able to provide significant antimicrobial activity, ensuring high biocompatibility, good chemical stability, and low toxicity. Such versatility has led to great success of this nanomaterial for antibacterial, antifungal, and, more recently, antiviral applications. However, methods for the preparation of ZnO NSs must be properly selected for their end use. Moreover, ZnO NSs can also be cytotoxic to some extent. In this context, this review emphasizes some aspects relevant to the preparation as well as to the antimicrobial use of ZnO NSs. In particular, a brief overview of the sol–gel, hydrothermal, biogenic, and electrochemical approaches proposed for their synthesis is presented, highlighting advantages/drawbacks of each route in terms of scalability, simplicity, and efficacy. Next, the application of ZnO NSs in several fields is reported. This is followed by a discussion of the antimicrobial role of ZnO NSs, where antimicrobial mechanisms of action, possible cell resistance, and cytotoxicity of ZnO NSs are highlighted. We also discuss the role of ZnO NSs against different biothreats, such as bacteria and viruses. The future of such nanomaterials in this application field is addressed in the final part.

show abstract

“…Although it is located far from impact area of the organism's defense systems, the inefficacy of the immune and other defense systems plays an important role in the arise of the disease (Lagowski et al, 2019). Besides, the humidity rate of the region, the deterioration of the keratinized tissue in the epidermis layer of the skin, zinc, vitamin A and D deficiencies are also important factors in the arise of the cases (Al-Janabi and Bashi, 2018;Çifci, 2018).…”

Section: Introductionmentioning

confidence: 99%

The Comparison of Ketokonazol and Hypochlorous Acid (Hocl) Applications for the Treatment of The Fungal Infections (Dermatophytosis)

Babur

Karademir

2023

Turkish JAF Sci.Tech.

View full text Add to dashboard Cite

Dermatophytosis is a mycotic disease of the skin that is resistant to treatment. The aim of this study was to investigate the treatment efficacy of a novel antimicrobial agent, Hypochlorous Acid (HOCL), on dermatophytosis of cats and dogs, in comparison with Ketaconazole. In this study, a total of 76 animals (26 cats and 50 dogs) without any disease other than skin fungal infection after clinical, hematological, biochemical, microscopic and Wood's lamp examinations were used. Subjects were randomly assigned to two equal treatment groups within their own species as HOCL: HP and Ketaconazole: KT. Naked eye inspection results were collected on the 8th, 11th and 15th days of all patients. The study was terminated on the 15th day by collecting the Wood's lamp and microscopic examination data together with the last inspection finding. Findings were analyzed statistically with chi-square and CART (Classification and Regression Tree) algorithm test. Inspection results of the treatment groups exhibited significant recovery over time (day 8, 11 and 15) for both species (p0.05). According to the microscopic examination results, a significant statistical difference was observed between the HP and KT groups (p0.05). As a result, it was concluded that HOCl has an effect on dermatophytosis of cat and dogs, although not as much as Ketaconazole, but further studies are needed to reveal the results more clearly.

show abstract

Development of a new synthetic xerogel nanoparticles of silver and zinc oxide against causative agents of dermatophytoses

Abstract: Xerogel nanoparticles composed of Ag and ZnO were successfully prepared. They had antidermatophytic action in specific concentrations.

Cited by 7 publications

References 18 publications

Zinc Therapy in Dermatology: A Review and Update

Zinc Therapy in Dermatology: A Review and Update

Synthesis and Antimicrobial Applications of ZnO Nanostructures: A Review

The Comparison of Ketokonazol and Hypochlorous Acid (Hocl) Applications for the Treatment of The Fungal Infections (Dermatophytosis)

Contact Info

Product

Resources

About