Development of a Preference-Based Index From the National Eye Institute Visual Function Questionnaire–25

Rentz, Anne M.; Kowalski, Jonathan W.; Walt, John G.; Hays, Ron D.; Brazier, John; Yu, R.; Lee, Paul; Bressler, Neil M.; Revicki, Dennis A.

doi:10.1001/jamaophthalmol.2013.7639

Cited by 42 publications

(44 citation statements)

References 44 publications

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“…The questionnaire is composed of 25 questions that evaluate various domains of quality of life and visual functioning, as outlined in Table 1 [4]. …”

Section: Methodsmentioning

confidence: 99%

“…The means were calculated according to the following equation: the mean is defined as the sum of the numerical values of each question within a given domain divided by the number of items evaluated in that domain [4]. …”

Section: Methodsmentioning

confidence: 99%

“…One important instrument is the 25-item Visual Functioning Questionnaire (VFQ-25) produced by the National Eye Institute (NEI) of the United States. The questionnaire measures the influence of low vision and visual symptoms on specific areas of overall health, such as the emotional state and social functioning [4]. …”

Section: Introductionmentioning

confidence: 99%

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Refractive and Quality of Vision Outcomes with Toric IOL Implantation in Low Astigmatism

Buscacio

Patrão²,

Moraes

2016

Journal of Ophthalmology

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Purpose. To evaluate the refractive and the quality of vision outcomes of toric IOL implantation in patients with low astigmatism. Design. Prospective study of single-arm. Methods. Patients with corneal astigmatism range from 0,75 D to 1,5 D and cataract that underwent cataract surgery with toric IOL. The measurements were performed preoperatively and 6 weeks after the surgery. Patients were evaluated for visual acuity with and without correction, contrast sensitivity, static and dynamic refraction, and quality of life questionnaire. Pre- and postoperative values were compared and their variations were evaluated for linear correlation. Results. 21 eyes of 21 patients. Postoperative mean uncorrected visual acuity was 0.80 ± 0.19, and the best corrected visual acuity was 0.97 ± 0.15. p < 0.001 compared to preoperative values. The average postoperative refractive cylinder was −0.34 ± 0.39. The questionnaire's total value before and after surgery was, respectively, 43.20 ± 15.76 and 79.70 ± 10.11 (p < 0.001). The correlation coefficients between the values of the questionnaire variation and the UCVA, BCVA, and CS variation were, respectively, 0.548 (p = 0.005), 0.508 (p = 0.009), and 0.409 (p = 0.033). Conclusion. Patients with low astigmatism who underwent phacoemulsification with toric IOL implantation experienced significant decrease in refractive astigmatism and improvement in their quality of life.

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“…The questionnaire is composed of 25 questions that evaluate various domains of quality of life and visual functioning, as outlined in Table 1 [4]. …”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Refractive and Quality of Vision Outcomes with Toric IOL Implantation in Low Astigmatism

Buscacio

Patrão²,

Moraes

2016

Journal of Ophthalmology

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“…26 One of the strengths of VRQoL measures is that they have the potential to integrate the multifaceted effects of disease on visual function. This ability makes the NEI-VFQ-25 and its corresponding preference-based index 27 potentially valuables tools for cost-effectiveness analyses by providing a method for capturing disease-specific trade-offs to complement the more commonly described general health trade-offs assessed using metrics such as the EQ-5D. However, the NEI-VFQ was not originally designed for patients with uveitis, so it may not be able to capture the impact on quality of life from disease-specific visual symptoms.…”

Section: Discussionmentioning

confidence: 99%

Longitudinal Vision-Related Quality of Life for Patients with Noninfectious Uveitis Treated with Fluocinolone Acetonide Implant or Systemic Corticosteroid Therapy

et al. 2017

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Purpose To evaluate longitudinal vision-related quality of life (VRQoL) in patients with noninfectious uveitis. Design Cohort study using randomized controlled trial data. Participants Patients with active or recently active intermediate uveitis, posterior uveitis, or panuveitis enrolled in the Multicenter Steroid Treatment Trial and Follow-up Study. Methods Data from the 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) for the first 3 years after randomization were evaluated semiannually. Analyses were stratified by assigned treatment (129 implant therapy vs. 126 systemic therapies) because of substantial differences in trajectories of VRQoL. The impact of baseline measurements of visual function (visual acuity and visual field), demographics, and disease characteristics was assessed using generalized estimating equations. Main Outcome Measures Primary outcome was the NEI-VFQ-25 composite score over 3 years after randomization. Results Individuals in both treatment groups showed similar improvement in NEI-VFQ-25 scores after 3 years of follow-up (implant: 11.9 points; 95% confidence interval [CI], 8.6–15.2; P < 0.001; systemic: 9.0 points; 95% CI, 5.6–12.3; P < 0.001; P = 0.21 for interaction). Individuals in the implant group showed a substantial improvement during the first 6 months followed by stable scores, whereas individuals in the systemic group showed a steady improvement over the course of follow-up. Worse initial visual acuity and visual fields were associated with lower initial NEI-VFQ-25 scores for both treatment groups. In the systemic group, these differences were maintained throughout follow-up. In the implant group, individuals with initial visual acuity worse than 20/40 showed additional improvement in NEI-VFQ-25 score to come within −7 points (95% CI, −15.0 to 0.9) of those with visual acuity 20/40 or better initially, a clinically meaningful but not statistically significant difference (P = 0.081). Results based on sensitivity analyses showed similar patterns. Conclusions Both treatment groups demonstrated significant improvements in NEI-VFQ-25 scores; however, the improvement was immediate for the implant group as opposed to gradual for the systemic group. Poorer visual function was associated significantly with initial differences in NEI-VFQ-25 scores. However, only individuals in the implant group with poor visual acuity were able to overcome their initial deficits by the end of 3 years.

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“…Rather than using individual dimension-levels as the independent variables in the regression analysis, these studies used corresponding Rasch logit values for health states to predict HSUVs. Two subsequent studies have used similar techniques to select a sample of health states [23] or predict HSUVs [35]. Although there remain some issues to resolve, particularly the ability of the technique to predict values for individual health states rather than groups of states based on total dimension-level scores [23], this is a promising new approach that is an important area for further research.…”

Section: Methods For Generating a Tariffmentioning

confidence: 99%

A Systematic Review of the Literature on the Development of Condition-Specific Preference-Based Measures of Health

Goodwin

Green

2016

Appl Health Econ Health Policy

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Background. Health state utility values (HSUVs) are required to calculate quality-adjusted life-years (QALYs). They are frequently derived from generic preference-based measures of health. However, such generic measures may not capture health attributes of relevance to specific conditions. In such cases, a condition-specific preference-based measure (CSPBM) may be more appropriate.Objective. This systematic review aimed to identify all published accounts of developing CSPBMs, to describe and appraise the methods used. Results. Eighty-six publications were identified, describing 51 CSPBMs. Around two-thirds of these were QALY measures; the remainder were designed for clinical decision-making only. Classification systems for 33 CSPBMs were derived from existing instruments; 18 were developed de novo. HSUVs for 34 instruments were estimated using a 'composite' approach, involving statistical modelling; the remainder used a 'decomposed' approach based on multi-attribute utility theory. Half of the papers that described the estimation of HSUVs did not report validating their measures.Conclusion. Various methods have been used at all stages of CSPBM development. The choice between developing a classification system de novo or from an existing instrument may depend on the availability of a suitable existing measure, while the choice between a decomposed or composite approach appears to be determined primarily by the purpose for which the instrument is designed. The validation of CSPBMs remains an area for further development. 3 Key Points for Decision MakersThere are two main approaches to developing a classification system (derivation from an existing instrument or de novo) and two main approaches to estimating health state utility values (using statistical regression or multi-attribute utility theory) for a condition-specific preference based measure.There is more evidence available to support the validity of classification systems that were derived from existing measures of health-related quality of life than there is for classification systems developed de novo.

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Development of a Preference-Based Index From the National Eye Institute Visual Function Questionnaire–25

Cited by 42 publications

References 44 publications

Refractive and Quality of Vision Outcomes with Toric IOL Implantation in Low Astigmatism

Refractive and Quality of Vision Outcomes with Toric IOL Implantation in Low Astigmatism

Longitudinal Vision-Related Quality of Life for Patients with Noninfectious Uveitis Treated with Fluocinolone Acetonide Implant or Systemic Corticosteroid Therapy

A Systematic Review of the Literature on the Development of Condition-Specific Preference-Based Measures of Health

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