Abstract:Background: Chronic respiratory impairment among older adults is associated with substation mortality, morbidity and was the third leading cause of death. Aim: Evaluate the effect of nursing intervention on ADL of older adults with chronic respiratory impairment. Design: A quasi-experimental design was used in this study. Sample: A purposive sample of 100 older adults patients with chronic respiratory impairment chosen from Government Hospital, half of them were study group and the other half was a control group. Tools: First: An interviewing questionnaire to assess demographic data, medical history and their knowledge. Second: An observational check list to assess their independency for activity of daily living. Third: A structured questionnaire to assess home environment. Results: Showed that there were highly statistical significant differences throughout intervention program phases (pre, post, and follow up) among the study group regarding their knowledge about chronic respiratory impairment, modify their home environment, and increase their independency level. The intervention had effect on their ADL, physical, psychological, and social conditions. Conclusion: There was a positive improvement compared with control group, and increasing the total satisfactory knowledge about chronic illness. Also increase the independency on practicing with ADL and enhancing psychological well-being among study group. The study recommended that: There is a need to increase of knowledge about; examination, checkup and follow up, simple modification of home environment to improve ventilation and degree of independence of daily activities such as bathing, grooming, dressing, precautions to infection prevention and social activities to improve the psychological status.