Development of a Questionnaire for the Assessment of Quality of Life in Korean Children With Allergic Rhinitis

Kim, Jeong Hee; Ahn, Young Mee; Kim, Hyung Jin; Lim, Dae Hyun; Son, Byong Kwan; Kang, Hee Suk; Song, Young Eun; Lee, Hee Young

doi:10.4168/aair.2014.6.6.541

Cited by 7 publications

(3 citation statements)

References 10 publications

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“…There have been some trials to assess the quality of life in Korean children with AR by questionnaires 3132. Contents of the questionnaire involved the degree of discomfort caused by main symptoms, daily activity or sleep disturbance, and psychosocial problems.…”

Section: Discussionmentioning

confidence: 99%

Comorbidities and Phenotypes of Rhinitis in Korean Children and Adolescents: A Cross-sectional, Multicenter Study

Lee

Yum

Sheen

et al. 2017

Allergy Asthma Immunol Res

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PurposeRhinitis is a nasal inflammatory disease in children and adolescents. However, little is known about the phenotypes and characteristics of allergic rhinitis (AR) in Korean children and adolescents. The objective of this study was to analyze the symptoms and comorbidities of rhinitis, to compare AR to non-allergic rhinitis (NAR), and to reveal the phenotypes and features of AR in a Korean pediatric population.MethodsPatients under 18 years of age with rhinitis symptoms were recruited from January 2013 to January 2015 by pediatric allergists. We analyzed symptoms, phenotypes, comorbidities, and allergen sensitization in this cross-sectional, multicenter study.ResultsMedical records were collected from 11 hospitals. The AR group has 641 (68.3%) patients, with 63.2% of boys and 7.5 (±3.4) years of mean age. The NAR group has 136 (14.5%) patients, with 55.1% of boys and 5.5 (±2.9) years of mean age. Moderate-severe persistent AR affected 41.2% of AR patients. Nasal obstruction was more common in NAR patients (P<0.050), whereas AR patients sneezed more (P<0.050) and more commonly had conjunctivitis, asthma, and otitis media (P<0.050). Sinusitis was the most common comorbidity in both groups. Allergen sensitization was caused by house dust mites (HDMs) (90.2%), pollen (38.7%), and animal dander (24.8%) in AR patients. Pollen and animal dander sensitization significantly increased age-dependently (P<0.050), but 91.9% of AR patients were already sensitized to HDMs before 5 years old.ConclusionsOur study revealed that AR was more prevalent than NAR and that 41.2% of AR presented with moderate-severe disease in Korean pediatric populations. Sinusitis was the most common comorbidity, and sleep disturbance was associated with the severity of rhinitis. The majority of AR patients were sensitized to HDMs in preschool ages. Further studies, including nationwide and longitudinal data, will help understand the relationship between these diseases.

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Section: Discussionmentioning

confidence: 99%

Comorbidities and Phenotypes of Rhinitis in Korean Children and Adolescents: A Cross-sectional, Multicenter Study

Lee

Yum

Sheen

et al. 2017

Allergy Asthma Immunol Res

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“…Nasal Index Score (NIS) was assessed; each of the 4 symptoms of nasal obstruction, rhinorrhea, sneezing, and nasal itching was subjectively assessed according to a grading scale from 0 to 3 (none=0; mild=1; obvious but tolerable=2; in-tolerable, affecting daily activities or sleep=3), with total scores ranging from 0 to 12 [12].…”

Section: Study Methodsmentioning

confidence: 99%

Exhaled Nitric Oxide and Symptom Severity in Children with Allergic Rhinitis

Kim¹,

Park²,

Moon³

et al. 2017

J Allergy Ther

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Objective: There have been few reliable biomarkers to evaluate allergic rhinitis (AR) severity in children. This study aimed to investigate a biomarker for assessing AR severity in children. Methods:A total of 107 children with AR (80) and non-allergic rhinitis (NAR, 27) were included in this study. The fraction of exhaled nitric oxide (FeNO) was measured and AR severity and duration was graded in patients with AR. We assessed the association between FeNO and the Allergic Rhinitis and its Impact on Asthma (ARIA) classes.Results: FeNO levels in the AR and NAR groups were 34.7 ± 22.1 and 17.0 ± 13.1 ppb, respectively (p=0.001). FeNO levels were significantly different (p<0.05) in the four ARIA classes: 14.3 ± 3.7 ppb in the mild intermittent group, 22.7 ± 4.8 ppb in the mild persistent group, 32.1 ± 16.1 ppb in the moderate-to-severe intermittent group, and 48.2 ± 25.2 ppb in the moderate-to-severe persistent group. We collapsed the 4 ARIA classes into 2 groups based on severity or duration. FeNO levels of the mild symptom group and moderate-to-severe symptom group were 18.7 ± 6.0 and 41.1 ± 23.0 ppb, respectively, which were significantly different (p=0.001). FeNO levels of the intermittent duration group (n=36) and persistent duration group (n=44) were 26.6 ± 15.9 and 41.2 ± 24.4 ppb, respectively, which were significantly different (p=0.001). Conclusion:FeNO levels were higher in children with increased severity and duration of AR. FeNO could be an indicator for classifying severity and evaluating treatment efficacy in children with AR.

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“…They can be expressed in many different organs, with variability of severity degrees, and in any age group, having a significant impact on the quality of life of patients and their families. 1 2 Every health professional can face them; however, they cannot be adequately tracked by international health classification and coding systems, such as the International Classification of Diseases (ICD). As an example, in 2012, we confirmed the under notification of anaphylaxis deaths due to difficult coding under the ICD-10 using the Brazilian national database, 3 which impacts the lack of epidemiological data to support public and private decision-making to offer appropriate treatment, such as auto-injectable adrenaline, still missing in some countries.…”

Section: Introductionmentioning

confidence: 99%

New Allergic and Hypersensitivity Conditions Section in the International Classification of Diseases-11

Tanno

Calderón

Demoly

et al. 2016

Allergy Asthma Immunol Res

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Allergy and hypersensitivity, originally perceived as rare and secondary disorders, are one of the fastest growing conditions worldwide, but not adequately tracked in international information systems, such as the International Classification of Diseases (ICD). Having allergic and hypersensitivity conditions classification able to capture conditions in health international information systems in a realistic manner is crucial to the identification of potential problems, and in a wider system, can identify contextually specific service deficiencies and provide the impetus for changes. Since 2013, an international collaboration of Allergy Academies has spent tremendous efforts to have a better and updated classification of allergies in the forthcoming International Classification of Diseases (ICD)-11 version, by providing scientific and technical evidences for the need for changes. The following bilateral discussions with the representatives of the ICD-11 revision, a simplification process was carried out. The new parented "Allergic and hypersensitivity conditions" section has been built under the "Disorders of the Immune System" chapter through the international collaboration of Allergy Academies and upon ICD WHO representatives support. The classification of allergic and hypersensitivity conditions has been updated through the ICD-11 revision and will allow the aggregation of reliable data to perform positive quality-improvements in health care systems worldwide.

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Development of a Questionnaire for the Assessment of Quality of Life in Korean Children With Allergic Rhinitis

Cited by 7 publications

References 10 publications

Comorbidities and Phenotypes of Rhinitis in Korean Children and Adolescents: A Cross-sectional, Multicenter Study

Comorbidities and Phenotypes of Rhinitis in Korean Children and Adolescents: A Cross-sectional, Multicenter Study

Exhaled Nitric Oxide and Symptom Severity in Children with Allergic Rhinitis

New Allergic and Hypersensitivity Conditions Section in the International Classification of Diseases-11

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