Development of a questionnaire survey to evaluate lower limb function of patients with knee osteoarthritis

Abstract

This study aimed to develop a self-questionnaire index relevant to lower limb functional assessment reflecting clinical symptoms and activity restrictions associated with activities of daily living (ADL) for patients with knee osteoarthritis. This cross-sectional study enrolled patients with knee osteoarthritis (Kellgren/Lawrence grade ≥ 1). Participants evaluated clinical symptoms and activity restrictions using self-reported questionnaires. Radiographic evaluation, knee joint range of motion (ROM), and lower limb muscle strength were assessed. Associations between clinical symptoms, activity restrictions, and knee and hip joint function were evaluated using multiple and logistic regression analysis. Overall, 142 participants were included in the final analysis. Patients with knee pain while rising from a chair had lower knee and hip extension strength (knee extension β = - 0.28; 95% confidence interval (CI), - 0.41 to - 0.14; P < 0.0001; hip extension β = - 0.26; 95% CI, - 0.42 to - 0.08; P = 0.0034), and restricted knee extension ROM (odds ratio [OR] = 2.17; 95% CI, 1.02-4.63; P = 0.041). Patients with knee pain during stair climbing, turning or who were unable to stand on one leg without external support had reduced hip abduction muscle strength (β = - 0.17; 95% CI, - 0.27 to - 0.07; P = 0.0008). Patients with knee pain while rising from a chair or stepping showed more severe knee joint degeneration on radiographic evaluation (OR = 3.26; 95% CI, 1.11-10.91; P = 0.03). The self-questionnaire index reflected clinical symptoms and activity restrictions associated with ADL and was significantly associated with lower limb function in individuals with knee osteoarthritis.

Effect of l‐Carnitine Supplementation on Osteoarthritis: A Systematic Review

“…The results of exercise therapy will have a big influence on how OA is treated. [ 36 ] Conversely, we recommend knee OA decompression surgery, including knee preservation surgery and total knee replacement, for patients who have not responded to conservative treatment.…”

Efficacy of virtual reality exercise in knee osteoarthritis rehabilitation: a systematic review and meta-analysis

“…Additionally, in our metaanalysis, improvement in flexor muscle strength was found to be more favorable compared to extensor muscle strength around the knee joint. It is worth noting that hip muscles also play a significant role in supporting stability and controlling movement of the knee joint, and during the progression of KOA, hip muscles may also experience pain and strength decline (Suzuki et al, 2019). Unfortunately, in the studies included in our analysis, there were no reports on the impact of VR training on hip muscle strength.…”