2010
DOI: 10.1248/cpb.58.875
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Development of a Quinazoline-Based Chelating Ligand for Zinc Ion and Its Application to Validation of a Zinc-Ion-Coordinated Compound

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Cited by 7 publications
(4 citation statements)
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“…Metal ions were screened in a similar manner as described in our previous reports [9][10][11]. Nineteen metal ions, namely Li(I), Cs(I), Ca(II), Sr(II), Ba(II), Cr(III), Mn(II), Fe(III), Fe(II), Co(II), Ni(II), Cu(II), Ag(I), Zn(II), Cd(II), Al(III), Pb(II), Bi(III), and Ga(III), were dissolved in water to a final concentration of 2.0 mmol L À1 .…”
Section: Screening Of Metal Ion Binding With Cpchmentioning
confidence: 99%
See 1 more Smart Citation
“…Metal ions were screened in a similar manner as described in our previous reports [9][10][11]. Nineteen metal ions, namely Li(I), Cs(I), Ca(II), Sr(II), Ba(II), Cr(III), Mn(II), Fe(III), Fe(II), Co(II), Ni(II), Cu(II), Ag(I), Zn(II), Cd(II), Al(III), Pb(II), Bi(III), and Ga(III), were dissolved in water to a final concentration of 2.0 mmol L À1 .…”
Section: Screening Of Metal Ion Binding With Cpchmentioning
confidence: 99%
“…Most functional ligands reported to date for the efficient capture of metal ions possess Schiff-base moieties in their structures [4][5][6][7][8]. In fact, in our laboratory, we have developed several chelating ligands with a Schiff-base moiety that can coordinate to metal ions such as Zn(II), Ga(III), and Sc(III) to emit fluorescence [9][10][11]. These chelating ligands have one or two Schiff-base moieties between two aromatic moieties such as quinazoline, vanilline, 2,4-dihydroxybenzene, and p-aminosalicylate [9][10][11].…”
Section: Introductionmentioning
confidence: 99%
“…In the Schiff base moiety, the lone pair on the nitrogen atom in the azomethine linkage coordinates the metal ions to form a complex. In our laboratory, three organic ligands with Schiff base moieties, 2,4-[bis-(2,4-dihydroxybenzylidene)]-dihydrazinoquinazoline (DBHQ) (Kimura et al 2009a, b), 2,4-[bis-(2-hydroxy-3-methoxybenzylidene)]-dihydrazinoquinazoline (HBQZ) (Yamada et al 2010), and 1-(2-hydroxy-3-methoxybenzaldehyde)-4-aminosalicylhydrazone (HMB-ASH) ( Fig. 1) (Yamada et al 2012), have been developed for the fluorescence detection of Ga(III), Zn(II), and Sc(III), respectively.…”
Section: Introductionmentioning
confidence: 99%
“…Specifically, 4-hydrazonylquinazolines in conjunction with the o-hydroxyazomethines of salicylaldehydes exhibited fluorescence selectively for Ga 3+ and Zn 2+ cations. [22][23][24] Our group has designed and synthesized 2-pyridinyl-methylene-4-hydrazone quinazoline transition metal complexes which exhibit DNA binding and photocleavage as well as antioxidant activities. 25,26 In addition, the above ligand was able to co-coordinate Zn 2+ metal ions with the non-steroidal anti-inflammatory drug diclofenac and these complexes possessed enhanced antioxidant and radical scavenger activities compared to the commercial drug.…”
mentioning
confidence: 99%