Development of a survey instrument to assess health-related quality of life in small animal cancer patients treated with chemotherapy

Iliopoulou, Maro; Kitchell, Barbara E.; Yuzbasiyan‐Gurkan, Vilma

doi:10.2460/javma.242.12.1679

Cited by 48 publications

(33 citation statements)

References 41 publications

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“…The veterinary surgeon and veterinary nurse should assess this and train and support caregivers in quality of life assessment. Several quality of life questionnaires for veterinary patients have been published and assessed and can be used to make objective and ongoing assessments of a patient's performance status (Wiseman-Orr and others 2004, Yazbek and Fantoni 2005, Lynch and others 2011, Crawford and others 2012, Iliopoulou and others 2013, Giuffrida and Kerrigan 2014). …”

Section: Quality Of Lifementioning

confidence: 99%

Palliative care in small animal oncology

Mason¹

2016

In Practice

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Cancer is a common diagnosis in companion animals and, increasingly, clients choose to pursue treatment for their pets. Veterinary oncology is a rapidly growing field and diagnostic and treatment options for animals with cancer are constantly improving and becoming more widely available. Treatment outcomes can be good, but in many cases definitive treatment is not an option and palliative treatment is necessary. This article explores the palliative care of dogs and cats that have been diagnosed with cancer and summarises the various treatment options, with a particular focus on quality of life and the role of communication in the decision-making process.

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Section: Quality Of Lifementioning

confidence: 99%

Palliative care in small animal oncology

Mason¹

2016

In Practice

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“…The World Health Organization (WHO) defines quality of life as; individual perception if their position in life in the context of the culture and value system in which they live and in relation to their goals, expectations, standards and concerns . Some studies have shown that disease severity and psychological stress affected on quality of life (Caffey et al, 1999;Farzianpour et al, 2012;Iliopoulou et al, 2013;Ovayolu et al, 2013). In other studies, quality of life has been linked to all factors of cancer disease including the type of treatment, type and severity of cancer (Bare and Smeltzer, 2004;Deng et al, 2013;Li et al, 2013;Ding et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Assessment of Quality of Life in Cancer Patients

Farzianpour¹

2014

American Journal of Agricultural and Biological Sciences

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Standards of Joint Commission International (JCI) emphasize on the organizational performance level in basic functional domains including patient right, patient care, medical safety and infection control. These standards are focused on two principles: Expectations of the actual organizational performance and assessment of organizational capabilities to provide high quality and safe Health Care Services (HCS). The aim of this study was to analyze the regression model of the Quality of Life (QOL) in cancer patients from Mazandaran province in 2013. This descriptive cross-sectional study was carried out on 185 cases after a chemotherapy treatment session during in the first three months that was referred to Rajaee Chemotherapy Center in 2013. The method of sampling was Purposive. General quality of life was assessed using WHO questionnaire (WHOQOL-BREF) and particular life quality was assessed using researcher-developed questionnaire. Data analysis was consisted of a multiple regression method and for comparison one-sample test of KolmogrovSmirnov was used. Statistical analysis showed that the average of general life quality, particular life quality and total average was evaluated, 1<0.96<5, 1<1.13<5 and 1<1.04<5, respectively. Due to the low quality of general and particular life, fully integration of the care program of patient care in primary health care system, easy access and facilitation in intervention to improve the quality of life is offered. Our motivation behind the research and the implications of the research was improvement of QOL cancer patients.

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“…As twothirds of canine gliomas occur in the forebrain, seizures and behavior changes are the most commonly reported clinical signs (23,28,29). In addition, healthrelated quality of life surveys for use in the assessment of clinical disability in dogs with cancer do exist, although the current iterations have not been specifically developed for or validated in dogs with brain tumors (30). The prognosis for dogs with gliomas is also poor, with death occurring weeks to months following diagnosis in the absence of treatment.…”

Section: Spontaneous Canine Gliomas As a Faithful Model Of Human Diseasementioning

confidence: 99%

Maximizing Local Access to Therapeutic Deliveries in Glioblastoma. Part V: Clinically Relevant Model for Testing New Therapeutic Approaches

Rossmeisl

2017

Glioblastoma

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A significant obstacle to the development of new brain tumor therapeutics remains the lack of rodent models that faithfully reproduce the in vivo complexities of human glioblastoma. Dogs and humans are the only species that frequently develop spontaneous brain tumors. Remarkable clinical, phenotypic, and molecular similarities exist between human and canine malignant glioma. Our research has focused on the development of pharmacologically tractable molecular targets common to human and canine gliomas, as well as the discovery Canine Brain Tumor Models 406 and refinement of novel methods of drug delivery to the brain, such as convection-enhanced delivery (CED), irreversible electroporation (IRE), and focused ultrasound, that can overcome the limitations imposed by the bloodbrain and blood-tumor barriers. Through the conduct of early phase clinical trials in dogs, we demonstrate the safety, feasibility, and preliminary efficacies of IL-13RA2-and EphA2-targeted bacterial cytotoxins and IRE for the treatment of spontaneous malignant glioma, illustrate the clinical utility of real-time imaging monitored CED as a robust drug delivery platform, and describe the use of the tumor-bearing dog in transcranial-focused ultrasound applications related to neuro-oncology. The dog brain cancer model offers unique opportunities to expedite the clinical translation of cancer therapeutics through the design of preclinical investigations that ask and answer drug and medical device development questions that cannot be sufficiently addressed in rodent models.

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Development of a survey instrument to assess health-related quality of life in small animal cancer patients treated with chemotherapy

Cited by 48 publications

References 41 publications

Palliative care in small animal oncology

Palliative care in small animal oncology

Assessment of Quality of Life in Cancer Patients

Maximizing Local Access to Therapeutic Deliveries in Glioblastoma. Part V: Clinically Relevant Model for Testing New Therapeutic Approaches

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