The conflict between indoor environmental quality and energy consumption has become an unneglectable problem for highrise office buildings, where occupants' productivity is highly affected by their working environment. An effective façade, therefore, should play the role of an active building skin by adapting to the ever-changing external environment and internal requirements. This paper explores the energy-saving and indoor environment-improving potential of a phase-change material (PCM) integrated façade. Building performance simulations, combined with parametric study and sensitivity analysis, are adopted in this research. The result quantifies the potential of a PCM-integrated façade with different configurations and PCM properties, taking as an example a south-oriented typical office room in Shanghai. It is found that a melting temperature of around 22•C for the PCM layer is optimal. Compared to a conventional façade, a PCM-integrated façade effectively reduces total energy use, peak heating/cooling load, and operative temperature fluctuation during the periods of May-July and November-December.