In order to study the thermoelectric properties of individual nanowires, a thermoelectric nanowire characterization platform (TNCP) has been previously developed and used in our chair. Here, we report on a redesigned platform aiming to optimize performance, mechanical stability and usability. We compare both platforms for electrical conductivity and the Seebeck coefficient for an individual Ag nanowire of the previously-used batch and for comparable measurement conditions. By this, the measurement performance of both designs can be investigated. As a result, whereas the electrical conductivity is comparable, the Seebeck coefficient shows a 50% deviation with respect to the previous studies. We discuss the possible effects of the platform design on the thermoelectric measurements. One reason for the deviation of the Seebeck coefficient is the design of the platform leading to temperature gradients along the bond pads. We further analyze the effect of bonding materials Au and Pt, as well as the effect of temperature distributions along the bond pads used for the thermovoltage acquisition. Another major reason for the variation of the measurement results is the non-homogeneous temperature distribution along the thermometer. We conclude that for the measurement of small Seebeck coefficients, an isothermal positioning of voltage-probing bond pads, as well as a constant temperature profile at the measurement zone are essential.