The development of necessary instrumentation and metrology at the nanoscale, especially fast, low-cost, and nondestructive metrology techniques, is of great significance for the realization of reliable and repeatable nanomanufacturing. In this work, we present the application of a homemade novel optical scatterometer called the tomographic Mueller-matrix scatterometer (TMS), for the measurement of photoresist gratings. The TMS adopts a dual rotating-compensator configuration and illuminates the nanostructure sequentially under test conditions by a plane wave, with varying illumination directions and records. For each illumination direction, the polarized scattered field along various directions of observation can be seen in the form of scattering Mueller matrices. That more scattering information is collected by TMS than conventional optical scatterometry ensures that it achieves better measurement sensitivity and accuracy. We also show the capability of TMS for determining both grating pitch and other structural parameters, which is incapable by current zeroth-order methods such as reflectometry-or ellipsometry-based scatterometry.With the ever-decreasing dimensions of advanced technology nodes (22 nm and beyond), there are also some challenges and limitations to optical scatterometry [10,11], such as the parameter correlation issue. In addition, optical scatterometry is mostly suitable for measuring repetitive dense structures, but infeasible for the measurement of isolated or generally non-periodic structures. To address the challenges or limitations in conventional optical scatterometry, several designs have been presented with the idea of trying to collect the scattering information about the nanostructure under test conditions as much as possible, such as with the goniometric optical scatter instrument [12][13][14], through-focus scanning optical microscopy [15], scatterfield microscopy [16], tomographic diffractive microscopy [17,18], and Fourier scatterometry [19,20]. Recently, we have also developed a novel instrument called the tomographic Mueller-matrix scatterometer (TMS) [21]. The TMS illuminates a sample sequentially by a plane wave with varying illumination directions (incidence angles 0 •~6 5.6 • and azimuthal angles 0 •~3 60 • ) and records. For each illumination direction, the polarized scattered filed along various directions of observation (scattering angles 0 •~6 7 • and azimuthal angles 0 •~3 60 • ) can be seen in form of scattering Mueller matrices. The experiments performed on a Si grating had preliminarily demonstrated the potential of a TMS in nanostructure metrology [21].Due to the strong correlation between pitch and other structural parameters, it is a common practice to predetermine grating pitch by another metrology tool such as AFM, or directly fix grating pitch to its nominal value in the solution of the inverse problem in optical scatterometry. In this work, we present the application of a TMS for the accurate reconstruction of lithographic patterns. We show the capability of a T...