The development of Printed Circuit boards (PCBs) has so far followed a traditional linear economy value chain, leading to high volumes of waste production and loss of value at the end-of-life. Consequentially, the electronics industry requires a transition to more sustainable practices. This review article presents an overview of the potential solutions and new opportunities that may arise from the greater use of emerging sustainable materials and resource-efficient manufacturing. A brief contextual summary about how the international management of Waste PCBs (WPCBs) and legalization have evolved over the past 20 years is presented along with a review of the existing materials used in PCBs. The environmental and human health assessment of these materials relative to their usage with PCBs is also explained. This enables the identification of which eco-friendly materials and new technologies will be needed to improve the sustainability of the industry. Following this, a comprehensive analysis of existing WPCB processing is presented. Finally, a detailed review of potential solutions is provided, which has been partitioned by the use of emerging sustainable materials and resource-efficient manufacturing. It is hoped that this discussion will transform existing manufacturing facilities and inform policies, which currently focus on waste management towards waste reduction and zero waste.