Development of an amperometric sulfite biosensor based on SOx/PBNPs/PPY modified ITO electrode

Rawal, Rachna; Pundir, C.S.

doi:10.1016/j.ijbiomac.2012.06.008

Cited by 32 publications

(11 citation statements)

References 36 publications

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“…At the same time, the linear portion at lower frequencies controls the diffusion event. [ 32 ] Randles equivalent circuit was used to fit the impedance spectra of the proposed immunosensor. This circuit contains electrolyte resistance ( R s ), Warburg impedance ( W ), charge transfer resistance ( R ct ), and constant phase element (CPI).…”

Section: Resultsmentioning

confidence: 99%

Electrochemical Immunosensor for Detection of CCR4 Cancer Biomarker in Human Serum: An Alternative Strategy for Modification of Disposable ITO Electrode

Aydın

Sezgintürk

2020

Macromolecular Bioscience

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Herein, a new strategy for the fabrication of a sensitive immunosensor capable of determination of CC Chemokine receptor 4 (CCR4) in complex serum samples is developed through the polymer modification on the disposable indium tin oxide electrode. Anti‐CCR4 antibodies, which are utilized as sensing biomolecules, are covalently attached on the succinimide groups of polypyrrole polymer (PPyr‐CSsg). The constructed immunosensor illustrates promising performances for the quantification of CCR4 antigen, with a linear detection range of 0.024–12 pg mL−1 and a low detection limit of 7.3 fg mL−1, calculated at a signal‐to‐noise ratio of 3. In addition, the impedimetric immunosensor displays a very successful analytical performance in terms of sensitivity, selectivity, repeatability, reproducibility, and long‐term stability as well as successful applicability for the accurate quantification of CCR4 in human serum samples. The constructed immunosensor is successfully used for quantification of CCR4 antigen in human serums. In addition, the immunosensor displays only 27.54% loss in its initial signal after nine weeks storage at 4 °C. Moreover, the fabricated immunosensor is economical, highly sensitive, and selective for CCR4 antigen detection, and suitable for potential application in clinical diagnosis.

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Section: Resultsmentioning

confidence: 99%

Electrochemical Immunosensor for Detection of CCR4 Cancer Biomarker in Human Serum: An Alternative Strategy for Modification of Disposable ITO Electrode

Aydın

Sezgintürk

2020

Macromolecular Bioscience

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“…Exceeding the consumption limit may cause headaches, nausea, diarrhea, asthma attacks, stomach irritation, nettle rash, and swelling. [15][16][17] Several methods for detecting sulfite such as iodometric titration, 18 high-performance liquid chromatography, 19 spectrophotometry, 20,21 chemiluminescence, 22 and capillary electrophoresis 23 have been developed. In contrast, these methods have various disadvantages such as time-consuming process, its high cost, and requirement for pretreatment of a sample.…”

Section: ¹mentioning

confidence: 99%

Electrochemical Detection for Sulfite Using Glassy Carbon Electrode Modified by Electrodeposition of Platinum Particles on Nitrogen-Containing Functional Groups

2020

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This study reports a novel electrochemical sensing technique based on electro-deposited Pt particles on glassy carbon electrodes modified with nitrogen atoms containing functional groups (PtNF-GC) electrode for detecting sulfite in aqueous solution. PtNF-GC electrodes have a favorable electrocatalytic activity of sulfite oxidation, which moves the oxidation peak potential to the negative direction of potential unlike Pt disk, a bare glassy carbon electrode and electro-deposited Pt particles on glassy carbon (Pt-GC) electrode. The linear relationship between the oxidation current peak and sulfite concentration is over the range up to 10 mM with a detection limit of 100 µM. Our prepared PtNF-GC electrode was applied for the sulfite detection in sample solution with favorite recovery of sulfite. Additionally, a possible reaction mechanism of sulfite was discussed.

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“…[3][4][5][6] Existence of accurate methods for determining sulfite is fundamental for the food industry to ensure product quality. At present, a number of analytical methods for detecting sulfite such as iodimetric titration, 7 high-performance liquid chromatography, 8 fluorescence, 9 chemiluminescence, 10 capillary electrophoresis, 11 and electrochemical detection 12,13 have been reported. Unlike these methods, electrochemical detection techniques realize simplicity, sensitivity, reliability, rapid detection, and also inexpensive.…”

Section: Introductionmentioning

confidence: 99%

Amperometric Sulfite Sensor Using Electrodecorated Pt Particles onto an Aminated Glassy Carbon Electrode Prepared by Stepwise Electrolysis

2020

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A novel modified glassy carbon electrode with platinum (Pt)-electrodecorated and nitrogen-containing functional groups was prepared by a stepwise electrolysis. The prepared electrode exhibited an electrocatalytic activity towards sulfite oxidation that was better than that of a bare glassy carbon electrode. The electrocatalytic activity of sulfite oxidation has been applied to an amperometric sulfite sensor. A favorable linear relationship between the current response (ΔI) and the sulfite concentration up to 500 M was exhibited. The detection limit was estimated to be 3 µM based on the criterion of signal-to-noise (S/N) ratio of 3 under optimized conditions. In regards to the reproducibility, the RSD (n= 10) was 8.9% for 80 µM sulfite.

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Development of an amperometric sulfite biosensor based on SOx/PBNPs/PPY modified ITO electrode

Cited by 32 publications

References 36 publications

Electrochemical Immunosensor for Detection of CCR4 Cancer Biomarker in Human Serum: An Alternative Strategy for Modification of Disposable ITO Electrode

Electrochemical Immunosensor for Detection of CCR4 Cancer Biomarker in Human Serum: An Alternative Strategy for Modification of Disposable ITO Electrode

Electrochemical Detection for Sulfite Using Glassy Carbon Electrode Modified by Electrodeposition of Platinum Particles on Nitrogen-Containing Functional Groups

Amperometric Sulfite Sensor Using Electrodecorated Pt Particles onto an Aminated Glassy Carbon Electrode Prepared by Stepwise Electrolysis

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