The aim of this study was to evaluate the effectiveness of the PLISSIT [Permission (P), Limited Information (LI), Specific Suggestions (SS) and Intensive Therapy (IT)] model in dealing with postpartum sexual problems. This was a quasi-experimental study with a pretest, a post-test and a control group made with 123 women (intervention=61; control=62). Before the application of the PLISSIT Model intervention plan, 77.0% of the women in the intervention group and 71.0% of the women in the control group had statistically similar 12 points or above scores of Arizona Sexual Experiences Scale-female form and sexual problems. After the application of the PLISSIT Model intervention plan, the women in the intervention group (60.7%) experienced statistically significant sexual problems according to the Arizona Sexual Experiences Scale-female form than the women in the control group (77.4%). This study revealed that the PLISSIT Model intervention plan reduced the postpartum sexual problems experienced by women.