2024
DOI: 10.12938/bmfh.2023-055
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Development of an improved colonization system for human-derived <i>Bifidobacterium longum</i> subsp. <i>longum</i> in conventional mice through the feeding of raffinose or 1-kestose

Mina SHIMADA,
Youhei KAWASE,
Kei SONOYAMA
et al.

Abstract: How bifidobacteria colonize and survive in the intestine is not fully understood. The administration of bifidobacteria to conventional mice can be used to evaluate their ability to colonize the intestine in the presence of endogenous gut microbiota. However, human-derived bifidobacteria do not readily colonize the intestines of conventional mice, and although colonization by Bifidobacterium breve UCC2003 has been achieved, the viability of such populations requires improvement. Therefore… Show more

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