Development of an in vivo radionuclide generator by labeling bleomycin with 191Os

Jamre, Mina; Salek, Nafise; Jalilian, Amir Reza; Moghaddam, L; Shamsaee, Mojtaba; Mazidi, Mohammad; Ghannadi‐Maragheh, Mohammad

doi:10.1007/s10967-011-1288-3

Cited by 6 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The biological removal half-times of activity from the liver and total body from Day 1 to 7 were estimated as 8 and 10 d, respectively. The study period was too short to determine any longer-term components of retention. (392) Biokinetic studies on rodents (Durbin et al., 1957; Durbin, 1960; Weininger et al., 1990; Jamre et al., 2011) indicate that the systemic behaviour of osmium is similar to that of platinum and the other members of the platinum group. The systemic distribution of osmium at 1 d after intravenous injection closely resembled that of platinum (Durbin et al., 1957; Durbin, 1960).…”

Section: Iridium (Z = 77)mentioning

confidence: 99%

ICRP Publication 137: Occupational Intakes of Radionuclides: Part 3

Paquet¹,

Bailey²,

Leggett³

et al. 2017

Ann ICRP

233

View full text Add to dashboard Cite

The 2007 Recommendations of the International Commission on Radiological Protection (ICRP, 2007) introduced changes that affect the calculation of effective dose, and implied a revision of the dose coefficients for internal exposure, published previously in the Publication 30 series (ICRP, 1979, 1980, 1981, 1988) and Publication 68 (ICRP, 1994). In addition, new data are now available that support an update of the radionuclide-specific information given in Publications 54 and 78 (ICRP, 1988a, 1997b) for the design of monitoring programmes and retrospective assessment of occupational internal doses. Provision of new biokinetic models, dose coefficients, monitoring methods, and bioassay data was performed by Committee 2, Task Group 21 on Internal Dosimetry, and Task Group 4 on Dose Calculations. A new series, the Occupational Intakes of Radionuclides (OIR) series, will replace the Publication 30 series and Publications 54, 68, and 78. OIR Part 1 has been issued (ICRP, 2015), and describes the assessment of internal occupational exposure to radionuclides, biokinetic and dosimetric models, methods of individual and workplace monitoring, and general aspects of retrospective dose assessment. OIR Part 2 (ICRP, 2016), this current publication and upcoming publications in the OIR series (Parts 4 and 5) provide data on individual elements and their radioisotopes, including information on chemical forms encountered in the workplace; a list of principal radioisotopes and their physical half-lives and decay modes; the parameter values of the reference biokinetic model; and data on monitoring techniques for the radioisotopes encountered most commonly in workplaces. Reviews of data on inhalation, ingestion, and systemic biokinetics are also provided for most of the elements. Dosimetric data provided in the printed publications of the OIR series include tables of committed effective dose per intake (Sv Bq−1 intake) for inhalation and ingestion, tables of committed effective dose per content (Sv Bq−1 measurement) for inhalation, and graphs of retention and excretion data per Bq intake for inhalation. These data are provided for all absorption types and for the most common isotope(s) of each element. The electronic annex that accompanies the OIR series of publications contains a comprehensive set of committed effective and equivalent dose coefficients, committed effective dose per content functions, and reference bioassay functions. Data are provided for inhalation, ingestion, and direct input to blood. This third publication in the series provides the above data for the following elements: ruthenium (Ru), antimony (Sb), tellurium (Te), iodine (I), caesium (Cs), barium (Ba), iridium (Ir), lead (Pb), bismuth (Bi), polonium (Po), radon (Rn), radium (Ra), thorium (Th), and uranium (U).

show abstract

Section: Iridium (Z = 77)mentioning

confidence: 99%

ICRP Publication 137: Occupational Intakes of Radionuclides: Part 3

Paquet¹,

Bailey²,

Leggett³

et al. 2017

Ann ICRP

233

View full text Add to dashboard Cite

show abstract

“…126 Some tracer development based on in vivo 191Os/191mIr generator for tumor imaging has also been performed in our laboratory. 127,128 Selenium-75 Selenium-75, a gamma-emitting isotope of selenium, is formerly used in labeling various compounds for SPECT imaging, including [ 75 Se]selenomethionine; however, the decay characteristics of selenium-75 are not ideal because of the high radiation dose delivered to the patient. It is now been mostly used in the production of standard sources for gamma camera calibration.…”

Section: Cobalt-57mentioning

confidence: 99%

Production and Clinical Applications of Radiopharmaceuticals and Medical Radioisotopes in Iran

Jalilian

Beiki

Hassanzadeh-Rad

et al. 2016

Seminars in Nuclear Medicine

View full text Add to dashboard Cite

“…relatively soluble forms (Durbin et al, 1957;Durbin, 1959;Moore et al, 1975a,b,c;Weininger et al, 1990;Jamre et al, 2011). ( 585) Highest concentrations of systemic osmium in rodents are typically seen in the kidneys and liver (Durbin et al, 1957;Durbin, 1959;Weininger et al, 1990;Jamre et al, 2011). Excretion is primarily in urine.…”

Section: Ingestionmentioning

confidence: 99%

“…Biokinetic data (597) The platinum group comprises six chemically similar elements generally found together in ores: platinum, iridium, ruthenium, rhodium, palladium, and osmium. Biokinetic studies on rodents indicate broadly similar biokinetics across the platinum group (Durbin et al, 1957;Durbin, 1959;Moore et al, 1975a;Weininger et al, 1990;Jamre et al, 2011).…”

Section: Monitoring Of Population Exposurementioning

confidence: 99%