In the last five years, the female labor force has increased rapidly in Saudi Arabia. This is due to the new government’s vision to empower women. For many decades, Saudi females were excluded from working in certain fields due to cultural restrictions. Nowadays, Saudi women are not only joining the service workforce but are currently employed in more physically demanding careers, such as manufacturing and military jobs, which were previously dominated by males. It becomes necessary to design workplaces, tools, and equipment to safely accommodate the female physical attributes, which include body dimensions. This study presents the anthropometric measurements of Saudi Arabian adult females. In total, 504 female subjects aged 20–70 participated in the study. Thirty-eight body measurements, including weight and triceps skinfold, were taken in sitting and standing postures. The main contribution of this study is to provide a national anthropometric database of Saudi females, which is very limited, especially for females in the age groups under study. The availability of such data will allow foreign and local manufacturers to design usable and safe products and workspaces for a wide range of Saudi adult females. The findings reveal that there are no significant differences in the body dimensions of Saudi females across all age groups, except for stature height, eye height, chest depth, skinfold (mm), sitting height, buttock–knee length, and hip breadth. The study also reveals that Saudi females’ body sizes are different from other Asian, Middle Eastern, and British nations, which invalidates the assumption of using other nations’ body measurements to estimate Saudis’ body measurements. Utilizing the supermarket cashier workstation to assess the appropriateness of commercial station fit for Saudi females’ body dimensions, the results underscore the crucial role of anthropometric measurements in addressing differences between product design and the unique body dimensions of Saudi females. The identified anthropometric mismatch highlights potential risks, emphasizing the threat to the working safety of Saudi females. Moreover, the data can be used by health professionals as a base to evaluate the health of Saudi adult females. Descriptive statistics and extreme values are determined. The data are presented in standard anthropometric tables.