Development of Antimicrobial Packaging Film Made from Poly(Lactic Acid) Incorporating Titanium Dioxide and Silver Nanoparticles

Abstract

Polylactide (PLA)/nano-TiO2 and PLA/nano-TiO2/nano-Ag blends films were prepared by a solvent volatilization method. Compared to pure PLA film, the nano-blend films have low water vapor permeability (WVP) and a poor transparency. With the increase of the NPs in the PLA, the tensile strength (TS) and elastic modulus (EM) decreased, while the elongation at break (ε) increased. SEM analysis indicated a rougher cross-section of the nano-blend films. According to the FTIR analysis, no new chemical bonds were formed in the nano-blend films. By using DSC to examine the crystallization and melting behavior, the result shows that the NPs have no effect on the glass transition (Tg) and melting temperature (Tm), but they caused an increase on the cold crystallization (Tc) and crystallinity (Xc). TGA results show that the addition of nanoparticles significantly improved the thermal stability. The PLA nano-blend films show a good antimicrobial activity against. E. coli and Listeria monocytogenes. Most important, we carried out migration tests, and verified that the release of NPs from the nano-blend films was within the standard limits.

Development of Bionanocomposites Based on PLA, Collagen and AgNPs and Characterization of Their Stability and In Vitro Biocompatibility

“…The addition of silver nanoparticles into PLA bionanocomposites up to 1 wt.% led to increase in the intensity of main absorption bands for PLA/AgNPs 0.5 and PLA/AgNPs 1 bionanocomposites. The same effect was observed in the case of polylactide (PLA)/nano-TiO 2 and PLA/nano-TiO 2 /nano-Ag blends films obtained by solvent casting [35]. This behavior can be explained by the presence of van der Waals interactions between the HO groups of PLA and the net atomic charge on the surface of the AgNPs [23] due to the asymmetric partition of electrons.…”

“…Our results revealed an increase of the T g and the degree of crystallinity of PLA with loading of AgNPs indicated that a small amount of AgNPs acts as a nucleating agent for increase the crystallinity of the plasticized PLA [36]. Another paper stipulated that the introduction of AgNPs had no significant effect on the T g of PLA samples [30,35], while an increase in T g value was observed in the case of PLA/cassava/GRH nanoplatelets [33]. The increase in the X c was also reported in the case of PLA/chitosan foam [14].…”

Thermal transitions and stability of melt mixed TiO2/Poly(L‐lactic acid) nanocomposites

“…Therefore, it can be concluded that the incorporation of TiO 2 nanoparticles in the PLLA matrix improves its thermal stability. Similar data have been reported by Li et al , who studied the nanocomposite film obtained by the addition of 1 and 5 wt% of nano‐TiO 2 to PLA. One of the possible reasons for this behavior is that TiO 2 nanoparticles may act as a heat barrier in the early stages of thermal decomposition , as well as that the incorporation of a heat‐resistant filler into the polymer matrix causes reduction in volatile degradation products, resulting in an increase of the thermal stability of the polymer composite .…”

Facile preparation of a novel biogenic silver-loaded Nanofilm with intrinsic anti-bacterial and oxidant scavenging activities for wound healing

“…in order to prepare flexible polylactic acid)/polyethylene glycol (PLA/PEG) (1:1) film 41 . Briefly, equal amounts of PLA and PEG (500 mg) were dissolved in dichloromethane (DCM) (40 ml) and stirred at 40 °C for 30 minutes with a magnetic stirrer.…”