Development of Biosignal Recording Board System with Agile Control of Circuit Characteristics for Various Biosignals

Ito, Kohei; Tani, Takaharu; Iwagami, Takuma; Nishino, Seiji; Kiyoyama, K.; Tanaka, Tetsu

doi:10.1002/ecj.12021

Cited by 5 publications

(2 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Figure 5A illustrates the bandwidth of an Ag/AgCl-gated p(g 3 C 2 T2-T) OECT, with an f c of 8.1 Hz in PBS and 234 Hz in IL. Since the effective frequency range of ECG is from 0.05 to 100 Hz, 34 the IL-gated OECT's bandwidth would retain all the signal components without loss. To verify this hypothesis, we connected an ECG simulator between the gate and the source of the OECT and monitored the I D in the presence of either electrolyte (Figure 5B).…”

Section: Since [Emim]mentioning

confidence: 99%

Ionic Liquid Gated Organic Electrochemical Transistors with Broadened Bandwidth

Zhong,

Nayak,

Wustoni

et al. 2023

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

The organic electrochemical transistor (OECT) is a biosignal transducer known for its high amplification but relatively slow operation. Here, we demonstrate that the use of an ionic liquid as the dielectric medium significantly improves the switching speed of a p-type enhancement-mode OECT, regardless of the gate electrode used. The OECT response time with the ionic liquid improves up to ca. 41-fold and 46-fold for the silver/silver chloride (Ag/AgCl) and gold (Au) gates, respectively, compared with devices gated with the phosphate buffered saline (PBS) solution. Notably, the transistor gain remains uncompromised, and its maximum is reached at lower voltages compared to those of PBS-gated devices with Ag/AgCl as the gate electrode. Through ultraviolet−visible spectroscopy and etching X-ray photoelectron spectroscopy characterizations, we reveal that the enhanced bandwidth is associated with the prediffused ionic liquid inside the polymer, leading to a higher doping level compared to PBS. Using the ionic liquidgated OECTs, we successfully detect electrocardiography (ECG) signals, which exhibit a complete waveform with well-distinguished features and a stable signal baseline. By integrating nonaqueous electrolytes that enhance the device bandwidth, we unlock the potential of enhancement-mode OECTs for physiological signal acquisition and other real-time biosignal monitoring applications.

show abstract

Section: Since [Emim]mentioning

confidence: 99%

Ionic Liquid Gated Organic Electrochemical Transistors with Broadened Bandwidth

Zhong,

Nayak,

Wustoni

et al. 2023

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

show abstract

“…Brain signals such as electroencephalography (EEG) and electrocorticography (ECoG) are used to diagnose epilepsy and have a very low amplitude between 1 μV and 5 mV. Other biological signals like ECG and electromyography have an amplitude that ranges from 100 μV to 5 mV . These waveforms need amplification before being processed by an analogue digital converter (ADC).…”

Section: Introductionmentioning

confidence: 99%

Implantable Neuroamplifers for Electrocorticography Using Flexible and Biocompatible Technology

Marcoleta

Nogueira

Yoma

et al. 2020

Physica Status Solidi (a)

View full text Add to dashboard Cite

Brain signals such as electroencephalography (EEG) and electrocorticography (ECoG) are used to diagnose epilepsy. ECoG signals are small and therefore require large amplification while keeping the recording electronics small enough to adapt to the surface of the brain. Moreover, the components have to be of low power to reduce the risk of brain damage while recording the brain. Herein, a neuroamplifier that is integrated in an ECoG is described. The amplifier, in combination with a novel multiplexing system that reduces the number of required amplifiers and ensures the flexibility of the ECoG, achieves the desired signal‐to‐noise ratio while reducing power consumption. The feasibility of the proposed design is validated though electronic simulations for different input signals, analyzing the actual amplification achieved and the response times. Moreover the circuit is implemented and real measurements are provided validating the simulations.

show abstract

Decoding Electrophysiological Signals with Organic Electrochemical Transistors

Zhong

Saleh

Inal

2021

Macromolecular Bioscience

View full text Add to dashboard Cite

The organic electrochemical transistor (OECT) has unique characteristics that distinguish it from other transistors and make it a promising electronic transducer of biological events. High transconductance, flexibility, and biocompatibility render OECTs ideal for detecting electrophysiological signals. Device properties such as transconductance, response time, and noise level should, however, be optimized to adapt to the needs of various application environments including in vitro cell culture, human skin, and inside of a living system. This review includes an overview of the origin of electrophysiological signals, the working principles of OECTs, and methods for performance optimization. While covering recent research examples of the use of OECTs in electrophysiology, a perspective is provided for next-generation bioelectric sensors and amplifiers for electrophysiology applications.

show abstract

Development of Biosignal Recording Board System with Agile Control of Circuit Characteristics for Various Biosignals

Cited by 5 publications

References 11 publications

Ionic Liquid Gated Organic Electrochemical Transistors with Broadened Bandwidth

Ionic Liquid Gated Organic Electrochemical Transistors with Broadened Bandwidth

Implantable Neuroamplifers for Electrocorticography Using Flexible and Biocompatible Technology

Decoding Electrophysiological Signals with Organic Electrochemical Transistors

Contact Info

Product

Resources

About