Controlled release formulations, used for the long-term preservation of pesticides, make agricultural development more precise, efficient, and safe. However, facile synthesis and high utilization of these formulations remain challenging. In this work, a polydopamine and metal−organic framework (MOF) hybrid was fabricated by a facile synthesis strategy for the controlled delivery of insecticide thiacloprid (THIA) and herbicide 2,4-D. The pesticides exhibited environment-responsive release behaviors. After 24 h, the cumulative release of THIA and 2,4-D reached 52.78 and 58.63% under alkaline conditions. The antiultraviolet photodegradation ability of THIA and 2,4-D increased nearly 4 times and 2 times, respectively. Significant insecticidal and herbicidal properties were observed