The use of orthopedic implants is increasing worldwide as the population of older people is growing. Metals and their alloys like stainless steel, cobalt-chromium alloys, and titanium alloys are widely used as implant biomaterials for the treatment of orthopedic joint failure because of their biocompatibility and good mechanical properties. However, these materials offer poor osseointegration due to their bio-inert nature. Hydroxyapatite, a bioactive material, has similar properties to bone tissue and helps in improving bone regeneration. It has good osseointegration properties, but it lacks mechanical properties. It has low fracture toughness, wear resistance and poor tensile strength. The carbon reinforced hydroxyapatite can have better mechanical properties as well as biocompatibility. The addition of graphene and carbon nanotubes in HA can also provide antibacterial effects and induce osteogenic differentiation of stem cells. The surface modification process like surface coatings involves the addition of composite materials to have desirable properties. The hydroxyapatite coatings produced by thermal spray are commercially accepted by FDA (Food and Drug Administration). Thermal spray materials can play a vital role in enhancing orthopedic implants' biocompatibility, wear, and corrosion resistance. The coatings can improve the optimal integration to the surrounding tissues and result in increasing the life of implants. The study will focus on the various thermal spray techniques like flame spray, HVOF (High-Velocity Oxygen Fuel), cold spray, and plasma spray that are commonly used in bio-implant applications. The paper will also discuss the different types of biomaterial coatings produced with thermal spray processes by the researchers. Moreover, the comparison of various thermal spray coatings for biomedical applications are also covered.