Cylinder lubrication oil is crucial in efficiently operating large two-stroke diesel engines. It manages mechanical friction and reduces wear on the cylinder liner and piston rings by creating a thin oil film between moving surfaces. To achieve this, the lubrication oil is delivered into the cylinder by a lubrication oil injector. This research focuses on a spray lubrication system that delivers the oil as a fine spray into the swirling scavenging air within the cylinder. This ensures coverage at the cylinder's top, where lubrication is critical. In recent years, there has been a growing emphasis on optimising lubrication oil consumption to lower the operational expenses of marine diesel engines. Thus far, these efforts have primarily relied on experimental trial and error methods, with limited numerical investigations into the intricacies of the spray injection process. This PhD thesis seeks to address this gap by exploring the scavenging air, spray breakup and other factors influencing the flow of cylinder lubrication oil through the injection nozzle and the subsequent spray formation, providing a deeper understanding for future research in this area.A Computational Fluid Dynamics (CFD) model is implemented using OpenFOAM's open-source software to simulate the scavenging process in a uni-flow two-stroke diesel engine. This model incorporates dynamic meshing to account for the influence of piston motion on the flow. The scavenging air simulation is validated against experimental data and other established CFD models. Additionally, lubrication oil sprays are introduced to the CFD model to provide insights into the movement of droplets in the scavenging air and their impact on the cylinder liner.To ensure an accurate representation of the oil injection rate during a single injection, the rate of injection is measured using the Bosch rate of injection technique. The experimental setup is tailored to accommodate the various shapes of the lubrication oil injectors. The experiments reveal a buildup time for the mass flow of approximately 1 ms until cavitation inside the nozzle starts to choke the flow. The experimental setup accurately predicts the injected mass in a single injection over a range of amounts with an error of about 5%. Experimental data from these experiments is used in the CFD model for simulating spray movement in the scavenging air. A parametric study is iii Preface Abbreviations Representation Representation ATDC After top dead centre BDC Bottom dead centre CAD Crank angle degree CFD Computational fluid dynamics CFL Courant-Friedrichs-Lewy CLS Cylinder lubrication system DNS Direct numerical simulation E-SIP Electronic -Swirl