In this paper, an unsteady investigation of the last two stages of a low-pressure steam turbine with supersonic airfoils near the tip of the last stage’s rotor blade is presented. Goal is the investigation of multistage effects and tip leakage flow in the last stage of the turbine and to provide insight on the stator-rotor flow interaction in the presence of a bow-shock wave. This study is unique in a sense of combining experimental data for code validation and comparison with a numerical simulation of the last two stages of a real steam turbine, including tip-cavity paths and seals, steam modelling and experimental data used as inlet and outlet boundary conditions. Analysis of results shows high unsteadiness close to the tip of the last stage, due to the presence of a bow-shock wave upstream of the rotor blade leading edge and its interaction with the upstream stator blades, but no boundary layer separation on stator is detected at any instant in time. The intensity of the shock wave is weakest, when the axial distance of the rotor leading edge from the upstream stator trailing edge is largest, since it has more space available to weaken. However, a phase shift between the maximum values of static pressure along the suction side of the stator blade is identified, due to the shock wave moving with the rotor blades. Additionally, the bow-shock wave interacts with the blade shroud and the tip leakage flow. Despite the interaction with the incoming flow, the total tip leakage mass flow ingested in the tip-cavity shows a steady behaviour with extremely low fluctuations in time. Finally, traces of upstream stage’s leakage flow have been identified in the last stage, contributing to entropy generation in inlet and outlet of last stage’s stator blade, highlighting the importance of performing multistage simulations.