Development of disseminated superficial porokeratosis in a patient with complicated acute pancreatitis

Ferreira, Olga; Duarte, A. Villodres; Baudrier, Teresa; Mota, Alberto; Azevedo, Filomena

doi:10.5070/d39410j0mf

Cited by 1 publication

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“…biologics [211][212][213][214][215][216][217], furosemide [218], antibiotics and benzylhydrochlorothiazide [180]). Other speculative triggers for DSP include acute pancreatitis [219], viral [197,220] and non-viral hepatitis [221,222] and diabetes mellitus (likely due to keratinocyte protein glycation) [137,175,191,223,224]. In a patient with diabetes mellitus treated using metformin and empagliflozin, bullous pemphigoid (BP) developed within the atrophic centres of DSP [225].…”

Section: Disseminated Superficial Porokeratosis (Dsp) 41 Clinical Pre...mentioning

confidence: 99%

Porokeratoses—A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants

Pietkiewicz,

Korecka,

Salwowska

et al. 2023

Metabolites

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Porokeratosis is a heterogeneous group of keratinising disorders characterised by the presence of particular microscopic structural changes, namely the presence of the cornoid lamella. This structure develops as a consequence of a defective isoprenoid pathway, critical for cholesterol synthesis. Commonly recognised variants include disseminated superficial actinic porokeratosis, disseminated superficial porokeratosis, porokeratosis of Mibelli, palmoplantar porokeratosis (including porokeratosis palmaris et plantaris disseminata and punctate porokeratosis), linear porokeratosis, verrucous porokeratosis (also known as genitogluteal porokeratosis), follicular porokeratosis and porokeratoma. Apart from the clinical presentation and epidemiology of each variant listed, this review aims at providing up-to-date information on the precise genetic background, introduces imaging methods facilitating the diagnosis (conventional and ultraviolet-induced fluorescence dermatoscopy, reflectance confocal microscopy and pathology), discusses their oncogenic potential and reviews the literature data on the efficacy of the treatment used, including the drugs directly targeting the isoprenoid–mevalonate pathway.

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Section: Disseminated Superficial Porokeratosis (Dsp) 41 Clinical Pre...mentioning

confidence: 99%

Porokeratoses—A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants

Pietkiewicz,

Korecka,

Salwowska

et al. 2023

Metabolites

View full text Add to dashboard Cite

show abstract

Development of disseminated superficial porokeratosis in a patient with complicated acute pancreatitis

Cited by 1 publication

References 0 publications

Porokeratoses—A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants

Porokeratoses—A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants

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