Development of Duodenal Ulcers due to the Discontinuation of Proton Pump Inhibitors After the Induction of Sofosbuvir Plus Ledipasvir Therapy: A Report of Two Cases
“…). Grade 3 or higher adverse events were not observed in the patients on DCV/ASV therapy, whereas duodenal ulcers due to discontinuation of proton pump inhibitor were observed in two patients on SOF/LDV therapy …”
Although further studies with a larger number of patients are required, we suggest that EBR/GZR therapy is an alternative therapy for patients with post-LT genotype 1 HCV re-infection.
“…). Grade 3 or higher adverse events were not observed in the patients on DCV/ASV therapy, whereas duodenal ulcers due to discontinuation of proton pump inhibitor were observed in two patients on SOF/LDV therapy …”
Although further studies with a larger number of patients are required, we suggest that EBR/GZR therapy is an alternative therapy for patients with post-LT genotype 1 HCV re-infection.
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