Development of Environmental Biosensors for Detection, Monitoring, and Assessment

Gupta, Shagun; Kakkar, Vipan

doi:10.1007/978-3-030-34544-0_7

Cited by 15 publications

(7 citation statements)

References 74 publications

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“… 9 , 10 The biosensor-based detection methods of pathogenic bacteria have gained attention due to their potential to offer relatively fast, portable, and easy-to-handle solutions. 11 In that context, various types of L. pneumophila biosensors have been investigated ranging from optical 12 , 13 and piezoelectric 14 , 15 to electrochemical. 16 , 17 However, to the best of our knowledge, an economically attractive method for automated monitoring of water reservoirs for the presence of pathogenic bacteria has yet to be developed.…”

Section: Introductionmentioning

confidence: 99%

“…In that context, various types of L. pneumophila biosensors have been investigated ranging from optical , and piezoelectric , to electrochemical. , However, to the best of our knowledge, an economically attractive method for automated monitoring of water reservoirs for the presence of pathogenic bacteria has yet to be developed. Recently, photoluminescence (PL)-based detection of E.…”

Section: Introductionmentioning

confidence: 99%

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Short Ligand, Cysteine-Modified Warnericin RK Antimicrobial Peptides Favor Highly Sensitive Detection of Legionella pneumophila

et al. 2021

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Culture-based methods for the detection of Legionella pneumophila are prohibitively slow and frequently inadequate. The problem has been addressed with biosensing technology that employs a variety of ligands for the specific capture of bacteria. However, the limited success of the application of mammalian antibodies, aptamers, and nucleic acid-based probes for sensitive biosensing has generated growing interest in exploring alternative biosensing architectures, such as those based on antimicrobial peptides (AMP) that are known for their attractive therapeutic applications. We report on the successful employment of cysteinemodified warnericin RK AMP for the operation of a highly sensitive biosensor of L. pneumophila based on digital photocorrosion of GaAs/AlGaAs nanoheterostructures. The replacement of the relatively cumbersome procedure commonly applied for the attachment of antibodies to COOH-terminated mercaptohexadecanoic acid self-assembled monolayers has allowed for a significant reduction in the distance at which bacteria are immobilized above the biosensor surface. An important consequence of this approach is the attractive limit of detection of L. pneumophila estimated at 2 × 10 2 CFU/mL. The target bacteria were captured four times more efficiently than P. fluorescens, B. subtilis, and E. coli, which is highly promising for environmental monitoring.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Short Ligand, Cysteine-Modified Warnericin RK Antimicrobial Peptides Favor Highly Sensitive Detection of Legionella pneumophila

et al. 2021

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“…Findings of scientific studies revealed that the biosensors can be used in agriculture (Dar et al 2020;Mufamadi and Sekhejane 2017) and to monitor different things in various components of the environment (Sha et al 2017;Gupta and Kakkar 2020;Bidmanova et al 2016;Saini et al 2019). Biosensors can also be used to prevent environmental damages and thus, it assists the stakeholders to comply with environment related legal provisions.…”

Section: Environmental Law Principlesmentioning

confidence: 99%

Biosensors: Ethical, Regulatory, and Legal Issues

Karim¹

2020

Handbook of Cell Biosensors

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The highest attainable standard of health is a fundamental human right as envisaged in important international human rights instruments. Biosensors have the prospect to introduce revolutionary changes in the promotion, preservation, and protection of human health, which are fundamental to enjoy other human rights. The biosensors are also promising in the monitoring of various components of the environment and biodiversity, and thus, can be used to attain some of the 2030 United Nations Sustainable Development Goals. With all the promises, there remain some legal, regulatory, and ethical challenges and concerns as well. This is because, in the different stages of the cradle-to-grave life cycle of scientific research and product development, many stakeholders are involved, and various legal and ethical issues evolve. While the ongoing R&D activities should be continued for the betterment of mankind, consideration of relevant ethical and legal issues should not be ignored. Various international and national bodies, having the authority to guide effective regulation and development of scientific

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“…The field can represent environmental characteristics such as chemical concentrations, light intensities, or heat. These two problems have various applications including environmental monitoring, source signal localization, exploration, hazardous regions mapping, and search and rescue [19], [21], [24], [29], [34].…”

Section: Introductionmentioning

confidence: 99%

A Distributed Active Perception Strategy for Source Seeking and Level Curve Tracking

Al-Abri

Zhang

2022

IEEE Trans. Automat. Contr.

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Algorithms for multi-agent systems to locate a source or to follow a desired level curve of spatially distributed scalar fields generally require sharing field measurements among the agents for gradient estimation. Yet, in this paper, we propose a distributed active perception strategy that enables swarms of various sizes and graph structures to perform source seeking and level curve tracking without the need to explicitly estimate the field gradient or explicitly share measurements. The proposed method utilizes a consensus-like Principal Component Analysis perception algorithm that does not require explicit communication in order to compute a local body frame. This body frame is used to design a distributed control law where each agent modulates its motion based only on its instantaneous field measurement. Several stability results are obtained within a singular perturbation framework which justifies the convergence and robustness of the strategy. Additionally, efficiency is validated through various computer simulations and robots implementation in 2-D scalar fields. The active perception strategy leverages the available local information and has the potential to be used in various applications such as modeling information propagation in biological and robotic swarms.

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Development of Environmental Biosensors for Detection, Monitoring, and Assessment

Cited by 15 publications

References 74 publications

Short Ligand, Cysteine-Modified Warnericin RK Antimicrobial Peptides Favor Highly Sensitive Detection of Legionella pneumophila

Short Ligand, Cysteine-Modified Warnericin RK Antimicrobial Peptides Favor Highly Sensitive Detection of Legionella pneumophila

Biosensors: Ethical, Regulatory, and Legal Issues

A Distributed Active Perception Strategy for Source Seeking and Level Curve Tracking

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