Development of Haematological Indices in Melanoma-bearing Liběchov Minipigs

Svoboda, Martin; Eichlerová, K.; Horák, Vratislav; Hrádecký, Jan

doi:10.2754/avb200574040603

Cited by 11 publications

(5 citation statements)

References 13 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3 Several non-genetic factors including castration (removal of testis, the source of testosterone) affecting haematological parameters of farm animals have been observed. 4,5 Castration means a process which stops the functions of the testes leading to sterilization. 6 The indications for castration are different according to reasons of castration such as to stop the production of male hormones and sperms, prevent mating after age of puberty, produce animal to be easier to handle with less aggressiveness, avoid unwanted pregnancies and mating of young females before they are of adequate body size and age for pregnancy and parturition and reduce goaty smell in males.…”

Section: Introductionmentioning

confidence: 99%

Comparison in haematological and biochemical changes in normal, acute and chronically castrated West African Dwarf goats

Olaifa

2018

Int J Res Med Sci

View full text Add to dashboard Cite

Background: Castration is one of the frequent management practices in large animal husbandry and burdizzo castration has been shown to produce fewer long-term behavioral signs of pain and distress than banding. Castration is known to reduce virility and aggression due to the elimination of testicular androgens. Methods: This is a comparative study of hematological and biochemical parameters in intact, acute and chronically castrated West African dwarf goats. Twelve adult West African Dwarf bucks weighing between 8 to 14 kg randomly divided into 3 groups of intact, acute and chronic castrated. They were castrated using burdizzo castrator. Hematological and biochemical parameters were estimated by standard laboratory procedures. Results: There were significant decreases (P<0.05) in the PCV, Hb, RBC, WBC and MCH of acute and chronically castrated goat compared to the control group. The MCV and platelets increased significantly in acute and chronically castrated goat; while the neutrophil and lymphocyte showed no significant changes. The result also showed no significant changes in Na , AST and Creatinine. Mg 2+ and ALT significantly increased in chronically castrated goats compared with the acutely castrated goats while Zinc increased significantly (P<0.05) in acute castrated compared with the control goats. Conclusions: Therefore, from this study, either acute or chronic castration in goats have no detrimental effect on blood electrolytes, but mainly deter the hematopoietic process in the animal owing to testosterone and androgen depletion in castrate animals.

show abstract

Section: Introductionmentioning

confidence: 99%

Comparison in haematological and biochemical changes in normal, acute and chronically castrated West African Dwarf goats

Olaifa

2018

Int J Res Med Sci

View full text Add to dashboard Cite

show abstract

“…There are various castration methods used in animals, which include physical, chemical and hormonal methods (Rajkumar, 2013).Haematological parameters are good indicators of the physiological status of animals (Khan and Zafar, 2005). Several non-genetic factors including castration affecting haematological parameters of farm animals have been observed (Svoboda et al, 2005;Xie et al, 2013). PCV, Hemoglobin concentration (Hb) and RBC were significantly reduced at 1, 2 and 3hours as compared to pre-castration level in this study.…”

Section: Discussionmentioning

confidence: 55%

Acute biochemical and Hematological responses to Burdizzo castration in West African Dwarf bucks

Kayode¹,

Obot²

2017

EJMR

View full text Add to dashboard Cite

Castration has been shown to elicit physiological stress, inflammatory reactions, pain-associated behaviour, suppression of immune function, and a reduction in performance to varying degrees. The responses to castration using Burdizzo were investigated in four male West African Dwarf (WAD) goats hourly over a period of 3 hours. The bucks were castrated with Burdizzo clamp, blood samples were collected by jugular venipuncture for biochemical, hematological and hormonal analyses. The hematological values showed significant decreases (P<0.05) in PCV, Hb, Rbc, neutrophil throughout the period, while the White blood cell count decreased significantly 1 hour post castration. Respiratory rate increased significantly (P<0.05) throughout the post castration period of study, while the rectal temperature significantly increasing (P<0.05) for just an hour post castration. Cortisol level rose significantly (P<0.05) throughout the study period. Testosterone and estrogen levels fell after an hour though non-significantly (P>0.05) but later rose significantly (P<0.05) during the second and third hour post castration. The serum biochemistry changes observed include a significant rise (P<0.05) in AST, ALT, urea and Creatinine after 1 hour upon castration, but the values later significantly decreased (P<0.05) after the 2nd and 3rd hours. The serum electrolytes increased significantly (P<0.05) an hour post castration when compared with the pre castration values and later decreased significantly (P<0.05) at the 2nd and 3 hours post castration in comparison to the 1st hour value. There was a non-significant (P>0.05) increase in heart rate 1 hour post castration before returning to the pre castration value. This study concluded that the effects of three hours post burdizzo castration on hematological and biochemical profile fluctuated significantly in all the values under study and this calls for clinical surveillance among surgeons when such animals are brought for surgery during the acute period of castration. Also, this study will make information available for clinicians and researchers.

show abstract

“…Lymphocytes count can be affected by many factors as diseases (Polaček et al, 2007); nutrition (Suchý et al, 2010;Havlík, et al 2011); stress and social status (Sutherland et al, 2006). Svoboda et al (2005) published content of lymphocytes in 2 weak old minipigs: 7.94 ± 2.87 G*l -1 . Šperanda et al (2006) evaluated percentage of lymphocyte of weaned piglets 29.16%, and in piglets, which were for 14 days fed with zearalenone contaminated feed in addition of clinoptilolite: 40.20 to 42.75%.…”

Section: Resultsmentioning

confidence: 99%

Development of leukocytes countin blood of neonatal pigs after colostrum intake

Rolinec¹,

Bíro²,

Šťastný³

et al. 2015

JCEA

View full text Add to dashboard Cite

The aim of this study was to analyze the development of white blood cells in blood of neonatal piglets immediately after birth and colostrum intake. Together 8 newborn piglets (Large white) were included in this study. Piglets were during whole experiment under his mother and the colostrum intake was ad libitum. Blood samples (1.0 mL) were collected before colostrum intake (0 hour) and on 3 rd , 6 th and 12 th hour after first colostrum intake. Heparinized blood samples were used for total white blood cells, lymphocytes, mid-sized cells and granulocytes determinations. Blood samples were analyzed using haematological analyser Abacus Junior Vet (Diatron, Austria). The results were statistically analyzed by a one-way ANOVA, the differences in average means of blood cells between different sampling times were tested with T-test. The content of white blood cells (P<0.01), lymphocytes (P<0.001), mid-sized cells (P<0.05) as well as granulocytes (P<0.05) changed statistically during the first 12 hours of piglets life. Only in the samples collected on 6 th and 12 th hour of piglets life, the white blood cells (11.68 resp. 10.82 G*l-1) and lymphocytes (8.13 resp. 9.63 G*l-1) reached the lower physiological range for pigs. Other white blood cells indices of neonatal piglets did not reach the lower limit of the reference range. However in all white blood cells indices, we detected very high differences between minimal and maximal values. It points out, that some newborn piglets had very low, whereas some newborn piglets had very high content of white blood indices and it suggest, that some piglets of the litter had better protection, whereas another piglets not.

show abstract

Development of Haematological Indices in Melanoma-bearing Liběchov Minipigs

Cited by 11 publications

References 13 publications

Comparison in haematological and biochemical changes in normal, acute and chronically castrated West African Dwarf goats

Comparison in haematological and biochemical changes in normal, acute and chronically castrated West African Dwarf goats

Acute biochemical and Hematological responses to Burdizzo castration in West African Dwarf bucks

Development of leukocytes countin blood of neonatal pigs after colostrum intake

Contact Info

Product

Resources

About