Lyophilized from plants extract is a process to prolong the amounts of phytochemicals in a solid form. The bioactive compound in LP, which is Gallic acid should be stable and bioavailable during the downstream processing such as drying process in order to achieve its optimum health benefits. Therefore, this study focuses on the impact of lyophilize methods such as spray drying followed by granulator method in order to determine the stability of bioactive compound in LP during drying and storage. After the powdered produce, it will test on the model of human digestion (dissolution study) either the amounts of phytochemicals still remain stable. Finally, shelf-life quality analysis and the dissolution rate (capsule size 0 and 1) were carried out. The results obtained show the methods employed in this study can be used for analysis of quality content and dissolution tests of LP capsules. For LB in shelf-life quality study, parameters for appearance and TYMC showed no significant difference after 3 months. For pH, the slight decrease in pH level will increase the number of TAMC in powder form. Compared to granule form, the pH level more consistent and the number of TAMC also in a control condition. The dissolution of capsules containing powder and granulated of LP showed a high percentage of bioactive compound released into the dissolution medium, although the bioactive compound content of herbal products (capsule size 1) was found to be half that of capsules size 0. Through observation for both capsules size content of LP, the maximum dissolution was achieved after 100 min.