Development of Hydrogel from Rice Bran Starch

Abstract

Wound dressing is a vital component of wound infection management specially by immunocompromised patients due to accidents that caused injuries. Biodegradable hydrogel-based wound dressings are being developed to acquire the advantage of high swelling capacity and being environment friendly at the same time. The study involves development of hydrogels using solution casting method with different ratio of rice bran starch. Mechanical properties such as tensile strength and swelling capacity were determined. The hydrogel developed with 7% starch emerged with comparable tensile strength and swelling capacity with the available wound dressing in the market. FT-IR spectra confirmed the crosslinking of PVA and starch while SEM images revealed that the hydrogel is not porous. Drug loading capacity of the hydrogel was determined to be 83.48% with PBS which is higher than with water. Results suggest that the developed hydrogel has great potential for wound dressing application with the advantage of being biodegradable.

Synthesis and Characterization of Novel Patchouli Essential Oil Loaded Starch-Based Hydrogel

“…The samples with conventional starch appeared more watery and with less networking compared with the waxy starch ones that showed more particularity and porosity. Similar results for pure starch hydrogels were obtained by [ 24 ], who prepared hydrogels from rice bran starch and obtained non porous hydrogels. The lack or limited porosity of the hydrogels could be advantageous, as it prevents the bacterial penetration that may lead to wound infection [ 25 ].…”