Development of in-situ produced CO2 switchable fatty acid microextraction based solidification of floating organic droplet for quantification of morin and quercetin in tea, vegetable and fruit juice samples by HPLC

Abdi, Khosrou; Ezoddin, Maryam; Alimoradi, Houman; Sadeghi, Ramezan

doi:10.1016/j.microc.2022.107197

Cited by 7 publications

(3 citation statements)

References 29 publications

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“…Quercetin (C15H10O7; Figure 1), a polyphenolic flavonoid phytochemical, is widely synthesized in plants. It is found in various plant species, including Amaryllidaceae, Brassicaceae, Capparaceae, Ericaceae, Liliaceae, and Rosaceae, as well as in fruits and vegetables [37][38][39][40].…”

Section: Overview Of Quercetinmentioning

confidence: 99%

A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms

Golmohammadi

Elmaghraby

Ramírez‐Coronel

et al. 2023

Fundamemntal Clinical Pharma

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Bladder cancer (BC) is known as a prevalent genitourinary malignancy and has a significant mortality rate worldwide. Despite recent therapeutic approaches, the recurrence rate is high, highlighting the need for a new strategy to reduce the BC cell progression. Quercetin, a flavonoid compound, demonstrated promising anticancer properties and could be used in the management of various malignancies such as BC. This comprehensive review summarized quercetin's cellular and molecular mechanisms underlying anticancer activities. The study's findings indicated that quercetin prevents the proliferation of the human BC cell line, promotes apoptosis of BIU‐87 cells, reduces the expression of p‐P70S6K, and induces apoptosis by p‐AMPK. Moreover, quercetin restricts tumor growth through the AMPK/mTOR cascade and prevents colony formation of human BC cells by triggering DNA damage. Studying this review article will help researchers better understand quercetin's functional role in the prevention and treatment of BC.

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Section: Overview Of Quercetinmentioning

confidence: 99%

A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms

Golmohammadi

Elmaghraby

Ramírez‐Coronel

et al. 2023

Fundamemntal Clinical Pharma

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“…The proper sample preparation protocol should now take *Correspondent: E-mail: girijabiotech@yahoo.co.in; sgirija@buc.edu.in International Journal of Food Science andTechnology 2024, 59, 3556-3572 doi:10.1111/ijfs.17043 Ó 2024 Institute of Food Science & Technology (IJFST) into account green analytical chemistry. The preparation of quercetin samples includes liquid-liquid extraction (LLE), supercritical fluid extraction (SFE), solvent extraction from solid samples and solid-phase extraction (Abdi et al, 2022). The cost, labour, time and environmental impact of these sample preparation methods is significant, with SFE being more environmentally friendly (Hamed et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

“…The proper sample preparation protocol should now take into account green analytical chemistry. The preparation of quercetin samples includes liquid–liquid extraction (LLE), supercritical fluid extraction (SFE), solvent extraction from solid samples and solid‐phase extraction (Abdi et al ., 2022). The cost, labour, time and environmental impact of these sample preparation methods is significant, with SFE being more environmentally friendly (Hamed et al ., 2023).…”

Section: Introductionmentioning

confidence: 99%

Efficient extraction methods and callus culture of quercetin from Indian white radish: yield analysis via HPLC quantification and assessment of cytotoxic activity

Balasubramanian,

Kumaraguru,

Girija

2024

Int J of Food Sci Tech

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SummaryIndian white radish Co. 1 (Raphanus sativus L.) contains medicinal quercetin, and its commercial value supports large‐scale quercetin isolation. Various extraction methods, including ultra‐assisted extraction (UAE), maceration extraction (ME), Soxhlet extraction (SE), conventional extraction (CSE) and serial maceration extraction (SME), were employed to extract quercetin from radish leaf sections. RP‐HPLC‐optimising key experimental parameters yielded a linear response for the individual target compounds in the concentration range, with a limit of quantification (LOQ) of 2.2 μg mL−1 (r2 = 0.9995), a limit of detection (LOD) of 2.2 μg per 1.0 g of crushed leaves and repeatability within the relative standard deviation (RSD) of 0.23–0.37%. For in vitro callus cultures, 2,4‐dichlorophenoxyacetic acid (2,4‐D), 6‐benzylaminopurine (BAP) and zeatin were used for callus induction from in vitro leaf segments of radish. MS medium enriched with 2,4‐D (0.5 mg) induced the highest percentage of callus at 4 weeks. Among the extraction methods, the SME method yielded the highest recovery of quercetin (96.9%; 1.92 mg g−1 DW), phenolic (26.07 mg g−1 DW) and flavonoid (34.03 mg g−1 DW), compared to other methods and solvents. The callus extract included 0.5 mg of 2,4‐D, 32.07 mg of phenolic, 42.03 mg of flavonoid and 6.46 mg of quercetin. The presence of phytocompounds and quercetin was confirmed by GC–MS/MS and RP‐HPLC. The isolated quercetin (57.9 μg) also showed lethal effects on HT‐29 human colon cancer cells. This method may be effective for evaluating quercetin in radish extracts.

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Direct solidification of switchable-hydrophilicity salicylic acid: A design for the on-site dispersive liquid-liquid microextraction of benzoylurea insecticides in water and honey samples

Wang

Hong

et al. 2023

Journal of Chromatography A

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Development of in-situ produced CO2 switchable fatty acid microextraction based solidification of floating organic droplet for quantification of morin and quercetin in tea, vegetable and fruit juice samples by HPLC

Cited by 7 publications

References 29 publications

A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms

A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms

Efficient extraction methods and callus culture of quercetin from Indian white radish: yield analysis via HPLC quantification and assessment of cytotoxic activity

Direct solidification of switchable-hydrophilicity salicylic acid: A design for the on-site dispersive liquid-liquid microextraction of benzoylurea insecticides in water and honey samples

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