Constructed in the late 1950s, the Transient Reactor Test facility (TREAT) provided numerous transient irradiations until operation was suspended in 1994. It was later refurbished, and resumed operations in 2017 to meet the data needs of a new era of nuclear fuel safety research. TREAT uses uranium oxide dispersed in graphite blocks to yield a core that affords strong negative temperature feedback. Automatically controlled, fast-acting transient control rods enable TREAT to safely perform extreme power maneuvers—ranging from prompt bursts to longer power ramps—to broadly support research on postulated accidents for many reactor types. TREAT’s experiment devices work in concert with the reactor to contain specimens, support in situ diagnostics, and provide desired test environments, thus yielding a uniquely versatile facility. This chapter summarizes TREAT’s design, history, current efforts, and future endeavors in the field of nuclear-heated fuel safety research.