Development of isotope dilution–liquid chromatography/tandem mass spectrometry as a candidate reference method for the accurate determination of patulin in apple products

Type B Trichothecenes in Cereal Grains and Their Products: Recent Advances on Occurrence, Toxicology, Analysis and Post-Harvest Decontamination Strategies

“…Worryingly, mycotoxins are not entirely eliminated throughout food processing operations and can also be detected in processed foodstuffs [ 3 , 4 ]. As reported by the Food and Agriculture Organization (FAO) of the United Nations, over 25% of globally produced cereal crops have been estimated to be contaminated with mycotoxins, thereby resulting in a loss of approximately one billion tons of foodstuffs annually [ 5 , 6 , 7 , 8 ]. Mycotoxin-contaminated food and feed can provoke serious acute and chronic health effects conjointly referred to as mycotoxicoses and these effects depend on various factors, such as toxicity level of contaminating mycotoxin, degree of exposure as well as the nutritional status of the individuals [ 8 , 9 ].…”

Development and validation of a label-free colorimetric aptasensor based on the HCR and hemin/G-quadruplex DNAzyme for the determination of patulin in fruits and fruit-based products from Xinjiang (China)

“…1,2 PAT is said to be the most important fruit toxin globally, and it is commonly found in contaminated fruits and fruit-based products. [3][4][5] Natural contamination of fruit products with PAT has been reported in many countries. [5][6][7][8][9] Toxicological studies have shown that PAT induces various health hazards to humans, and is implicated in many acute and chronic disturbances.…”

“…The most widely applied contemporary methods for PAT determination in food samples are high performance liquid chromatography (HPLC) coupled to an ultraviolet (UV) detector, 16 liquid chromatography-tandem mass spectrometry (LC-MS/MS), 4,17 and gas chromatography-mass spectrometry (GC-MS). 18 These methods can detect the target PAT with satisfactory stability and high sensitivity.…”