Development of Macrovascular Diseases in NIDDM Patients in Northern Taiwan: A 4-yr follow-up study

Abstract

In the prevention of macrovascular diseases, effective intervention of the nondiabetic cardiovascular risk factors may be as important as or even more important than the good control of diabetes.

Body mass index and waist circumference as determinants of coronary artery disease in Taiwanese adults with type 2 diabetes mellitus

“…Although the lack of an association between smoking and CAD seemed to be contradictory to the generally accepted concept of smoking as a risk factor, no association was also noted in our previous longitudinal follow-up study for CAD incidence in patients with T2DM in Taiwan. 18 More studies are necessary to examine this somewhat interesting but paradoxical finding. The results of this study also suggested the usefulness of using WC to approximate visceral adiposity due to its significant association with CAD in the diabetic patients.…”

“…[18][19] CAD was defined by Minnesota codes of coronary probable (1.1, 1.2, 7.1) and coronary possible (…”

“…13 Reliable and convincing evidence of clinical relevance to apply the cutoffs recommended by the IOTF or by the DOH for the Taiwanese population is still lacking. It is also unknown whether these cutoffs can predict CAD in Taiwanese patients with type 2 diabetes mellitus (T2DM), a subgroup of subjects with the highest risk of cardiovascular morbidity [14][15][16][17][18][19] and mortality. 1 Therefore, the purpose of the present study was to determine the optimal cutoffs of BMI and WC as determinants for CAD in Taiwanese adults with T2DM.…”

Non-insulin-dependent diabetes and its metabolic control are important predictors of stroke in elderly subjects.

“…'-8 - 9 Moreover, there are no prospective population-based studies evaluating metabolic control and duration of diabetes as predictors of stroke in elderly diabetic subjects. Disturbances in glucose metabolism are characterized not only by hyperglycemia but also by hyperinsulinemia, which has been found to be a risk factor for coronary heart disease in some 1011 but not all 12 studies.…”

Hypertension is the Most Important Component of Metabolic Syndrome in the Association With Ischemic Heart Disease in Taiwanese Type 2 Diabetic Patients

“…19,20 The lack of an association in the present study (Tables 1 and 5) was consistent with our previous follow-up study for IHD incidence in patients with T2DM. 14 The effect of smoking might be more important in younger individuals than in the elderly. [21][22][23] Therefore the role of smoking on IHD in the diabetic patients with an average age of approximately 60 years in Taiwan requires further confirmation.…”