Development of Medical and Technical Requirements and Simulation of the Flow−Pressure Characteristics of the Sputnik Pediatric Rotary Blood Pump

Denisov, M. V.; Селищев, С. В.; Telyshev, D. V.; Frolova, E. A.

doi:10.1007/s10527-017-9641-7

Cited by 12 publications

(8 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This way the flow must be evenly distributed between the pulmonary arteries, considering the reduction of the system power loss with the RBP connected for the auxiliary blood circulation. The analysis carried out in this work and many similar studies performed by other groups [19][20][21][23][24][25] shows that the blood flow in TCPC is formed by the flow geometry configuration. First, as it is shown for TCPC-1 and TCPC-2 configurations, the blood flow coming from IVC is mixed directly with the flow from the SVC at the TCPC junction.…”

Section: Discussionsupporting

confidence: 67%

“…The analysis carried out in this work and many similar studies performed by other groups shows that the blood flow in TCPC is formed by the flow geometry configuration. First, as it is shown for TCPC‐1 and TCPC‐2 configurations, the blood flow coming from IVC is mixed directly with the flow from the SVC at the TCPC junction.…”

Section: Discussionsupporting

confidence: 57%

“…Preparation of the pump geometric model as a support for patients with TCPC was based on previous experience in the development of auxiliary blood circulation systems. [18][19][20][21] The pump consists of two stationary parts: the diffuser flow and the straightener with three blades, and one moving part--the impeller. All components are located in the flow tube.…”

Section: Geometric Model Of the Pumpmentioning

confidence: 99%

“…These pumps due to their size can anatomically fit to patients with a univentricular heart. One example of such devices is the pediatric rotary blood pump (PRBP) called Sputnik which was recently developed by our research group . The aim of this study is to investigate the hemodynamics of the flow in the region of PRBP and the bypass connection.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Energetics of blood flow in Fontan circulation under VAD support

et al. 2019

View full text Add to dashboard Cite

The need to simulate the normal operating conditions of the human body is the key factor in every study and engineering process of bioelectronic devices designed for implantation. The Fontan procedure is an example of such a process aimed to support the human body function. It is a standard treatment method for patients with a functionally univentricular heart. However, it has significant drawbacks such as overload of the only functional heart ventricle that often leads to the necessity of the heart transplantation. In this study, we analyze the total cavopulmonary connection (TCPC) influence on the blood with and without connected auxiliary blood circulation pump. We investigate four different types of TCPC configurations, analyze blood pressure and different flow rate, study the turbulent kinetic energy distribution, and evaluate hydraulic and power losses for various cases. Finally, we calculate volumetric scalar shear stresses distribution and demonstrate the high potential of TCPC configuration with connected rotary pump as a tool for the load redistribution in the functional heart ventricle. This work is particularly relevant for improving existing TCPCs’ quality that can extend the life of Fontan patients. Moreover, it also applies to the reduction of morbidity and mortality of the patients waiting for the heart transplantation.

show abstract

Section: Discussionsupporting

confidence: 67%

Section: Discussionsupporting

confidence: 57%

Section: Geometric Model Of the Pumpmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Energetics of blood flow in Fontan circulation under VAD support

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The authors noted that the lowest rotation speed necessary to maintain the hemodynamics appropriate for a young child could cause clot formation. This is the principal reason for using a VAD outside its operating ranges, which causes fundamental changes to blood flow in the pump leading to the formation of backflows and stasis zones and resultant thrombus formation .…”

mentioning

confidence: 99%

The Progress in the Novel Pediatric Rotary Blood Pump Sputnik Development

et al. 2018

View full text Add to dashboard Cite

In this work, the study results of an implantable pediatric rotary blood pump (PRBP) are presented. They show the results of the numerical simulation of fluid flow rates in the pump. The determination method of the backflows and stagnation regions is represented. The operating points corresponding to fluid flow rates of 1, 3, and 5 L/min for 75-80 mm Hg pressure head are investigated. The study results have shown that use of the pump in the 1 L/min operating point can potentially lead to the appearance of backflows and stagnation regions. In the case of using pumps in fluid flow rates ranging from 3 to 5 L/min, the number of stagnation regions decreases and the fluid flow rate changes marginally. Using the pump in this flow rate range is considered judicious. The study shows an increase in shear stress with an increase in fluid flow rates, while there is no increase in shear stress above the critical condition of 150 Pa (which does not allow us to reliably speak about the increased risk of blood cell damage). The aim of this work was to design, prototype, and study interaction of the Sputnik PRBP with the cardiovascular system. A three-dimensional model of Sputnik PRBP was designed with the following geometrical specifications: flow unit length of 51.5 mm, flow unit diameter of 10 mm, and spacing between the rotor and housing of 0.1 mm. Computational fluid dynamics studies were used to calculate head pressure-flow rate (H-Q) curves at rotor speeds ranging from 10 000 to 14 000 rpm (R = 0.866 between numerical simulation and experiment) and comparing flow patterns at various points of the flow rate operating range (1, 3, and 5 L/min) for operating pressures ranging from 75 to 80 mm Hg. It is noted that when fluid flow rate changes from 1 L/min to 3 L/min, significant changes are observed in the distribution of zero flow zones. At the inlet and outlet of the pump, when going to the operating point of 3 L/min, zones of stagnation become minuscule. The shear stress distribution was calculated along the pump volume. The volume in which shear stress exceed 150 Pa is less than 0.38% of the total pump volume at flow rates of 1, 3, and 5 L/min. In this study, a mock circulatory system (MCS) allowing simulation of physiological cardiovascular characteristics was used to investigate the interaction of the Sputnik PRBP with the cardiovascular system. MCS allows reproducing the Frank-Starling autoregulation mechanism of the heart. PRBP behavior was tested in the speed range of 6 000 to 15 000 rpm. Decreased contractility can be expressed in a stroke volume decrease approximately from 18 to 4 mL and ventricle systolic pressure decrease approximately from 92 to 20 mm Hg. The left ventricle becomes fully supported at a pump speed of 10 000 rpm. At a pump speed of 14 000 rpm, the left ventricle goes into a suction state in which fluid almost does not accumulate in the ventricle and only passes through it to the pump. The proposed PRBP showed potential for improved clinical outcomes in pediatric patients with a body surface area g...

show abstract