Simultaneous interpreting (SI) is difficult to reduce to an efficient and ecologically valid experimental paradigm allowing the measurement of working memory (WM) and attention-key components of all cognitive models of SI. These models could be validated and further refined in light of electrophysiological evidence. Here we propose a novel method for estimating WM load and report the results of our electroencephalographic study that lend support to the prediction of the Efforts Model of SI (Gile, 1988). In particular, this model predicts that increased WM load impairs the processing of auditory stimuli. Consistent with the model, the P1 and N1 components, elicited by task-irrelevant tone probes embedded in the source message and used as an index of attention, were significantly modulated as a function of WM load but not the direction of interpretation. Negativity in the P1/N1 range decreased at higher values of WM load, suggesting shallower processing of the source message under high WM load regardless of the direction.