Development of mosquito repellant gel formulations from various natural volatile oils: comparative study with the marketed formulation odomos®

Shivhare, Ruchi S.; Kamble, Manish A.; Mahapatra, Debarshi Kar; Ingole, Ashwini; Baheti, Jagdish

doi:10.22270/jddt.v8i6.2031

Cited by 8 publications

(8 citation statements)

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“…It means that the corporation of citronella oil into lotion increased protection time by 65 minutes. However, combining citronellal oil with some other essential oils (Eucalyptus globulus, Murraya Koenigii, C. citratus, Tridex procumbens, and Azadirachta indica) and formulating them into a gel does not improve repellent activity (Shivhare et al 2018) compared to the present study.…”

Section: Repellent Activitycontrasting

confidence: 86%

“…One of the biological activities of citronella oil is a repellent activity which is the ability to resist the landing or biting of insects on human or animal skin (Nerio et al 2010;Ranasinghe et al 2016;Shivhare et al 2018;Yadav et al 2014). Female mosquitos Aedes aegypti is a vector of dengue fever disease that threatens life (Soonwera 2015).…”

Section: Introductionmentioning

confidence: 99%

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Essential oil from Cymbopogon nardus and repellant activity against Aedes aegypti

2020

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Abstract. Arpiwi NL, Muksin IK, Kartini NL. 2020. Essential oil from Cymbopogon nardus and repellant activity against Aedes aegypti. Biodiversitas 21: 3873-3878. Cymbopogon nardus (L.) Rendle is an aromatic grass from the Poaceae family that produces essential oil mainly in the leaves. The essential oil from C. nardus is known as citronella oil has repellent activity. This research aimed to quantify the oil content of C. nardus leaves, to analyze the essential oil quality, to analyze the repellent activity of lotion with different concentrations of citronella oil against Aedes aegypti, and to examine the quality of formulated lotions. The oil was extracted from leaves using steam distillation, and the quality was examined according to the Indonesian National Standard. The citronella oil was formulated into a lotion with five concentrations (0, 2, 3, 4, 5% w/w). Repellent activity of the lotions against Ae. aegypti was tested using screened cage test method under laboratory conditions. Lotion quality was analyzed for pH, viscosity, homogeneity, and sensorial assessments. The result showed that the oil yield of C. nardus leaves was 0.9% w/w. The color of the oil was pale yellow, specific weight was 0.8819, the refraction index was 1.464, total geraniol was 72.71%, citronellal content was 49.14%, and solubility in 80% alcohol 1:2 was clear. The repellent activity of lotions with citronella oil was concentration-dependent, where a concentration of 5% gave the highest protection. The quality of formulated lotions met the standard and the lotions were nonirritant.

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Section: Repellent Activitycontrasting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Essential oil from Cymbopogon nardus and repellant activity against Aedes aegypti

2020

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“…The smoothness of the gel was evaluated by simply rubbing the formulation between fingers to feel for smoothness, clumps, roughness, and homogeneity [16].…”

Section: Evaluation Of Emulgel Formulation Physical Evaluationmentioning

confidence: 99%

“…1 g of the formulated gel was dissolved in 25 mL of distilled water. The measurement of pH was performed in triplicate and the average reading was calculated [16].…”

Section: Phmentioning

confidence: 99%

Development of Herbal Mosquito-Repellent Formulations and Their Comparative Evaluation

PJ,

SUSHMA,

SRIJA

2023

Asian J Pharm Clin Res

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Objective: The present research work aimed to develop herbal mosquito repellents as gels, incense sticks, and liquids for plug-in devices and also to assess their performance characteristics. Methods: Herbal materials possessing mosquito-repellent activity were selected from the literature review based on percentage repellency and protection period. In this study, lavender, rosemary, lemongrass, and cedarwood oils were selected as actives. Span 20 and tween 80 were used to emulsify the volatile materials and then incorporated into Carbopol 934 base to form F1 and F2 gels which were evaluated for homogeneity, pH, spread ability, viscosity, and extrudability. Incense sticks were developed using charcoal and jigat as base materials. The prepared incense sticks F3 and F4 were evaluated for burning time, ash weight, and smoke. Solutions F5 and F6 were prepared using surfactants and cosolvents and were evaluated for phase separation. All formulations were screened for their mosquito repellency by screen cage method and their performance was compared to that of the marketed herbal repellents. Results: Reared mosquitoes were identified as Culex species by microscopical observations of the antenna and maxillary palps. Mosquito repellency in 4 h is 93%, 87%, 89%, 79%, 89%, and 85% for F1, F2, F3, F4, F5 and F6, respectively. Among all, gel formulation F1 expressed the highest mosquito-repellent activity with 93% and is a better candidate. Conclusions: Gel, incense sticks, and liquids prepared for use in plug-in devices exhibited reasonably good percentage repellency comparable to that of the standard. All the developed formulations are suitable for indoor protection from mosquito bites. However, safety, stability, and field studies need to be carried out to demonstrate suitability for regular use.

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“…Regarding sensitivity traits and other rash or response symptoms, a complete evaluation was conducted. The program was followed for seven days straight, and evaluations were completed [19].…”

Section: Washabilitymentioning

confidence: 99%

Development and Characterization of Medicated Ointment Containing Extracts of Dolichos biflorus, Cichorium intybus, Pterocarpus marsupium, and Crataeva nurvala

Kumar¹,

Raman²,

Rathore³

et al. 2022

IJMPS

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The present research reflected towards exploring the plausible role(s) of extracts of Dolichos biflorus (seed), Cichorium intybus (root), Pterocarpus marsupium (bark), and Crataeva nurvala (bark) formulated as ointment product. The formulations were characterized by determining the pharmaceutical characteristics like pH, skin irritancy test, viscosity, appearance, extrudability, spreadability, washability, and swelling index. No specific edema or erythema symptoms were seen following treatment for a continuous seven days according to the skin irritation test investigation. The formulations’ pH levels were determined to be 5.2 (F1) and 5.7 (F2). F1 displayed swelling of 1.29%, whereas F2 displayed swelling of 1.14%. The spreadability of the two ointment formulations (F1 and F2) was 6.9 g.cm/sec and 5.2 g.cm/sec. For F1 and F2, the extrudability of the formulations from the collapsible tubes was determined to be +++ and ++, respectively. The viscosity was determined to be 4550 cps (F1) and 5300 cps (F2) when examining the rheological features of the formulations. The formulations’ washability was determined to be +++ for Formulation-1 and ++ for Formulation-2. The uses of polyherbal formulations in conventional medicine were revealed by this discovery, which also revitalized the concepts of ethnopharmacology in relation to contemporary medicine.

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Development of mosquito repellant gel formulations from various natural volatile oils: comparative study with the marketed formulation odomos®

Cited by 8 publications

References 0 publications

Essential oil from Cymbopogon nardus and repellant activity against Aedes aegypti

Essential oil from Cymbopogon nardus and repellant activity against Aedes aegypti

Development of Herbal Mosquito-Repellent Formulations and Their Comparative Evaluation

Development and Characterization of Medicated Ointment Containing Extracts of Dolichos biflorus, Cichorium intybus, Pterocarpus marsupium, and Crataeva nurvala

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