Development of novel paper-based electrochemical device modified with CdSe/CdS magic-sized quantum dots and application for the sensing of dopamine

França, Caio César Lima de; Meneses, Diógenes; Silva, Anielle Christine Almeida; Dantas, Noélio O.; Abreu, Fabiane Caxico de; Petroni, Jacqueline Marques; Lucca, Bruno Gabriel

doi:10.1016/j.electacta.2020.137486

Cited by 43 publications

(9 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our research group recently explored, for the first time, the application of MSQDs for the modification of electrochemical sensors [37]. This pioneering work proposed a simple and inexpensive paper electrochemical device (PED) whose carbon-based working electrode was modified with CdSe/CdS MSQDs.…”

Section: Nanocrystals To Biosensors Improvementmentioning

confidence: 99%

NanoBioSensors: From Electrochemical Sensors Improvement to Theranostic Applications

Silva¹,

Alvin²,

Jesus³

et al. 2022

Biomedical Engineering

Self Cite

View full text Add to dashboard Cite

This chapter comments on the advantages of nanobiosensors using nanocrystals in improving electrochemical sensors’ response and their use as theragnostic tools in biomedical applications. The use of nanomaterials to modify electrochemical sensors’ surfaces to increase these devices’ sensitivity and their bio-functionality enables high-quality nanotechnological platforms. Thus, graphene nanostructures and CdSe/CdS magic-sized quantum dots (MSQDs) were shown to improve biosensor’s sensitivity. In addition, the use of CdSe/CdS MSQDs and cobalt ferrite nanocrystals (NCs) as potential tools for drug delivery systems and biocompatible titanium dioxide NCs in osseointegration processes and their bio-location are also demonstrated. So, this chapter shows some impressive results on which the group has been working regarding the applications of nanocrystals to electrochemical sensors and theranostic applications.

show abstract

Section: Nanocrystals To Biosensors Improvementmentioning

confidence: 99%

NanoBioSensors: From Electrochemical Sensors Improvement to Theranostic Applications

Silva¹,

Alvin²,

Jesus³

et al. 2022

Biomedical Engineering

Self Cite

View full text Add to dashboard Cite

show abstract

“…Silva et al demonstrated that the CdSe/ CdS MSQDs could be bioconjugated with several biomolecules aiming at the most diverse luminescent probes [38][39][40][41][42] in biosensors. [43,44] Dias et al labeled a phospholipase A2 isolated from Bothrops alternatus snake venom with CdSe/CdS MSQDs to track it in myoblast culture, making it possible to identify the bioconjugate on the surface of the plasma membrane and in the nuclear region. [39] Figure 7 corroborates these data since it is possible to observe fluorescence markings only in myoblasts treated with the bioconjugate MSQDs-BaltPla2.…”

Section: Nanocrystals As Luminescent Markers (Nanomarkers)mentioning

confidence: 99%

“…[34,35] Silva et al demonstrated that the biocompatibility of CdSe/CdS MSQRd could be tuned in the synthesis, [36] present high luminescence stability in biological systems [37], can be bioconjugated with several biomolecules aiming at the most diverse luminescent probes [38][39][40][41][42] and in biosensors. [43,44] This chapter shows recent results that the group has been working with fluorescent reporter proteins and the applicability of nanocrystals as fluorescent markers. Nanocrystals of pure and europium doped TiO 2 and CdSe/CdS (MSQDs) will be some of the exciting tools for marking in biological systems.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Markers: Proteins and Nanocrystals

Silva¹,

Oliveira²,

Silva³

et al. 2021

Bioluminescence - Technology and Biology

View full text Add to dashboard Cite

This book chapter will comment on fluorescent reporter proteins and nanocrystals’ applicability as fluorescent markers. Fluorescent reporter proteins in the Drosophila model system offer a degree of specificity that allows monitoring cellular and biochemical phenomena in vivo, such as autophagy, mitophagy, and changes in the redox state of cells. Titanium dioxide (TiO2) nanocrystals (NCs) have several biological applications and emit in the ultraviolet, with doping of europium ions can be visualized in the red luminescence. Therefore, it is possible to monitor nanocrystals in biological systems using different emission channels. CdSe/CdS magic-sized quantum dots (MSQDs) show high luminescence stability in biological systems and can be bioconjugated with biological molecules. Therefore, this chapter will show exciting results of the group using fluorescent proteins and nanocrystals in biological systems.

show abstract

“…[17,18] Furthermore, conductive paper can aid in the immobilization of sensitive materials on the surface and strengthen the substrate surface's efficiency and sustainability due to the highly strong and stable bonding between surface and material. Various nanomaterials such as reduced graphene oxide (rGO), [19][20][21][22] carbon nanotubes, [23][24][25][26] quantum dots, [27][28][29][30] nanoparticles [31][32][33][34][35] and conductive polymers, [17,36,37] etc. has been used to modify the paper surface to increase the conductivity.…”

Section: Introductionmentioning

confidence: 99%

Reduced Graphene Oxide‐Gold Nanoparticle Nanohybrid Modified Cost‐Effective Paper‐Based Biosensor for Procalcitonin Detection

2022

View full text Add to dashboard Cite

The present study reports the fabrication of reduced graphene oxide (rGO)/gold nanoparticles (AuNP) nanocomposites modified cellulose fiber paper-based electrochemical biosensor for procalcitonin (PCT) biomarker detection. PCT is a biomarker specific for bacterial infection (BI) detection and has gained much attention as a potential solution to the problems associated with determining appropriate antibiotic use. In sepsis and other severe infections, serum PCT levels increase to values above 100 ng mL À 1 in response to pro-inflammatory stimulation. The structural and morphological characterization of the rGO-AuNP composite are investigated using UV-Vis spectroscopy, FTIR spectroscopy, X-ray diffraction, and scanning electron microscopy. Monoclonal antibodies specific to PCT were covalently immobilized onto the rGO-AuNP nanocomposite modified paper to fabricate an electrochemical biosensor. The fabricated biosensor exhibits linearity in the PCT concentration range 10 À 15 × 10 3 pg mL À 1 , with a low detection limit 10 pg mL À 1 . Furthermore, the proposed biosensor also exhibited good selectivity and could detect PCT biomarkers even in the presence of other interfering electroactive species such as glucose, oxalic acid, and urea. The proposed CF-based biosensor has been proven as an accelerated simple point-ofcare (POC) exploratory approach for early PCT diagnosis in inadequate areas with limited production facilities, computational techniques, and highly skilled experts.

show abstract

Development of novel paper-based electrochemical device modified with CdSe/CdS magic-sized quantum dots and application for the sensing of dopamine

Cited by 43 publications

References 49 publications

NanoBioSensors: From Electrochemical Sensors Improvement to Theranostic Applications

NanoBioSensors: From Electrochemical Sensors Improvement to Theranostic Applications

Fluorescent Markers: Proteins and Nanocrystals

Reduced Graphene Oxide‐Gold Nanoparticle Nanohybrid Modified Cost‐Effective Paper‐Based Biosensor for Procalcitonin Detection

Contact Info

Product

Resources

About