“…They are the primary farmed species, by volume of production, and characterised by cost-intensive farming for the investment for seed, feed, drugs, other chemicals, and labour that created a large domestic market with export potentials involving a large number of stakeholders across their value-chains. In farming of these species, the feed conversion ratio (FCR) is 2.0, and the cost of feed accounts for over 70 % of the total operating cost [ 3 ]. Previous studies have reported that feed is contaminated with various harmful substances, such as antibiotics, heavy metals, hormones, mycotoxins, organophosphates, anthelmintics and dyes [ 5 , 6 ].…”