MES 2022
DOI: 10.47183/mes.2022.003
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Development of PCR test for detection of the SARS-CoV-2 genetic variants alpha, beta, gamma, delta

Abstract: The emergence of novel SARS-CoV-2 genetic variants with increased transmissivity and reduced antibody neutralization efficiency is a threat to global public health. Reverse transcription polymerase chain reaction (RT-PCR) with the use of fluorescent probes, which make it possible to detect the single nucleotide substitutions, is a technique suitable for screening the SARS-CoV-2 RNA-containing samples for the already known functionally significant mutations in the S-gene, identification of which allows to defin… Show more

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“…Once this variant appeared in Russia, it spread quickly. In July 2021, in Moscow and the Moscow Region, the proportion of Delta variant SARS-COV-2 cases was over 99% [ 35 ].…”
Section: Discussionmentioning
confidence: 99%
“…Once this variant appeared in Russia, it spread quickly. In July 2021, in Moscow and the Moscow Region, the proportion of Delta variant SARS-COV-2 cases was over 99% [ 35 ].…”
Section: Discussionmentioning
confidence: 99%