The force-displacement behavior of the Friction Pendulum ™ (FP) bearing is a function of the coefficient of sliding friction, axial load on the bearing and effective radius of the sliding surface. The coefficient of friction varies during the course of an earthquake with sliding velocity, axial pressure and temperature at the sliding surface. The velocity and axial pressure on the bearing depend on the response of the superstructure to the earthquake shaking. The temperature at an instant in time during earthquake shaking is a function of the histories of the coefficient of friction, sliding velocity and axial pressure, and the travel path of the slider on the sliding surface. A unified framework accommodating the complex interdependence of the coefficient of friction, sliding velocity, axial pressure and temperature is presented for implementation in nonlinear response-history analysis. Expressions to define the relationship between the coefficient of friction and sliding velocity, axial pressure, and temperature are proposed, based on available experimental data. Response-history analyses are performed on FP bearings with a range of geometrical and liner mechanical properties and static axial pressure. Friction is described using five different models that consider the dependence of the coefficient of friction on axial pressure, sliding velocity and temperature. Frictional heating is the most important factor that influences the maximum displacement of the isolation system and floor spectral demands if the static axial pressure is high. Isolation system displacements are not significantly affected by considerations of the influence of axial pressure and velocity on the coefficient of friction.