Development of pharmacognostical parameters and estimation of quercetin using HPTLC in leaves of Nelumbo nucifera Gaertn

Jain, Reshma; Rajput, Sadhana J.

doi:10.5530/pj.2012.34.6

Cited by 5 publications

(4 citation statements)

References 6 publications

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“…Precision and accuracy studies were done by taking 12 determinations (4 concentrations/3 replicates each). Samples at four different concentration levels (20,40,60 and 80 ng/band for CMN and 100, 200, 300, 400 ng/band for QCN) were applied in hexplicate on the same day. Sample concentration was estimated from the calibration curve.…”

Section: Resultsmentioning

confidence: 99%

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HPLC and HPTLC methods for Simultaneous Estimation of Quercetin and Curcumin in Polyherbal Formulation

Baghel¹,

Nagar²,

Pannu³

et al. 2017

Journal of Pharmaceutical Sciences

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Baghel, et al.: Chromatographic Analysis of Quercetin and CurcuminFast, sensitive, precise and selective high performance liquid chromatography and high performance thin layer chromatography methods were developed for the simultaneous estimation of curcumin and quercetin in a polyherbal formulation. Validation of these methods were carried out with respect to linearity, range, precision, accuracy and robustness. Both methods were applied to a polyherbal formulation to find the amount of curcumin and quercetin and compared. Curcumin and quercetin were found to be 9.5 mg and 0.613 mg in the polyherbal formulation using the high-performance liquid chromatography method whereas with the high performance thin layer chromatography method, curcumin and quercetin were found to be 9.7 mg and 0.674 mg, respectively. Both methods identified and quantified curcumin and quercetin effectively.

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Section: Resultsmentioning

confidence: 99%

“…Estimation of QCN has been done by using HPTLC for a number of times individually and also in combination with other compounds [20][21][22][23] . Also a number of validated HPLC methods have been devised for the estimation of QCN both individually and in combination with other compounds [24][25][26][27] .…”

Section: Research Papermentioning

confidence: 99%

HPLC and HPTLC methods for Simultaneous Estimation of Quercetin and Curcumin in Polyherbal Formulation

Baghel¹,

Nagar²,

Pannu³

et al. 2017

Journal of Pharmaceutical Sciences

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“…There are many reports in the literature where pharmacognostic study of leaves of different plants is reported eg. Melaleuca leucadendron [27] , Nelumbo nucifera, [28] Manilkara zapota, [29] Eucalyptus globulus, [30] Cinnamomum verum, [31] Terminalia catappa, [32] Psidium guajava [33] and Polyalthia longifolia. [34] In conclusion, these parameters are reported for the first time for P. pinnata leaf.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical and pharmacognostic evaluation of leaves of Pongamia pinnata L. (Fabaceae)

Menpara¹,

Chanda²

2014

Phcog Commn.

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“…Quercetin is well known for its antioxidant qualities and has been investigated for significant health benefits [53,54]. Antioxidant characteristics may help protect skin cells from oxidative stress and damage.…”

Section: Descriptionmentioning

confidence: 99%

Design and Development of Nanoemulsion of Smilax China for Anti-Psoriasis Activity

BODKE,

KUMBHAR,

BELWALKAR

et al. 2024

Int J Pharm Pharm Sci

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Objective: The present investigation aimed to prepare a smilax china loaded nanoemulsion using tween 80 as a surfactant and propylene glycol as a co-surfactant. Formulation of such drugs in nanoparticulate drug delivery will be advantageous for reducing dosing frequency, longer residence time, improved permeation, and patient compliance. Methods: High-speed homogenization method. The smilax china oil was prepared by collecting the extract of smilax china leaves into the coconut oil and then used as a solvent. The authentication studies of smilax china and coconut oil were evaluated for their organoleptic and physicochemical characteristics. The quantitative estimation and pre-formulation study of quercetin was carried out which has major anti-psoriatic properties. Surfactant and co-surfactant were selected and the solubility studies of oil and Surfactants were done. The nanoemulsion was characterized by particle size, polydispersity index, zeta potential, and entrapment efficiency (%). Results: This nanoemulsion provides the particle size and entrapment efficiency range between 80.52 to 89.78 nm and 68.66 to 70.16 % respectively. Batch SC1 showed the lowest particle size, PDI, and optimized drug entrapment effectiveness (%), indicating good particle size consistency within the remaining formulation batches. The optimized formulation SC 1 was found to be stable for 90 d. Conclusion: The formulated nanoemulsion showed significant antipsoriasis activity due to the presence of quercetin which has a rhetorical yield of 1.066 mg per 5 gm powder of smilax china leaves. Formulated smilax china-loaded nanoemulsion, has the potential as an effective antipsoriasis agent with a good spreading property with faster absorption which is beneficial for reducing drug concentration with maximum therapeutic effect.

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Development of pharmacognostical parameters and estimation of quercetin using HPTLC in leaves of Nelumbo nucifera Gaertn

Cited by 5 publications

References 6 publications

HPLC and HPTLC methods for Simultaneous Estimation of Quercetin and Curcumin in Polyherbal Formulation

HPLC and HPTLC methods for Simultaneous Estimation of Quercetin and Curcumin in Polyherbal Formulation

Phytochemical and pharmacognostic evaluation of leaves of Pongamia pinnata L. (Fabaceae)

Design and Development of Nanoemulsion of Smilax China for Anti-Psoriasis Activity

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