Development of Poly(Lactic Acid)/Chitosan Co-Matrix Microspheres: Controlled Release of Taxol-Heparin for Preventing Restenosis

Chandy, Thomas; Rao, Gundu H. R.; Wilson, Robert F.; Das, Gladwin S.

doi:10.1080/107175401750177025

Cited by 25 publications

(1 citation statement)

References 29 publications

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“…The advent of novel polymers and their use in drug delivery systems have achieved great development in the last two decades. Polymeric drug delivery can be a drug in micro-or nanocapsules as a formulation or a device that enables the introduction of a therapeutic substance into the body [4,5] . The major advantages of using controlled delivery systems can include the maintenance of drug levels within a desired range, the need for fewer administrations, optimal use of the desired drug, and increased patient compliance [2,3] .…”

Section: Remarkablementioning

confidence: 99%

Connected polymeric drug delivery systems: A promise for the future!

Chandy

2023

J. Polym. Sci. Eng.

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Subcutaneous (SC) drug delivery is one of the best routes of drug administration to patients over intravenous (IV) administration due to the ease of application and patient acceptance. The main limitation of using the SC route is administering larger volumes of drug, greater than 3–5 mL for therapeutic dosages. Wearable injectors on body devices are an attractive option for larger-volume drug delivery to patients. Thus, the need for a self-administration strategy at home is growing faster and is required for the next level of time-dependent and high-volume drug delivery. The advances in low-cost, connected on-body delivery systems hold great opportunity for novel ways of delivering home-based drug therapy in the future.

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