Development of porous silver nanoparticle/polycaprolactone/polyvinyl alcohol coatings for prophylaxis in titanium interconnected samples for dental implants

Versatile Biodegradable Poly(acrylic acid)-Based Hydrogels Infiltrated in Porous Titanium Implants to Improve the Biofunctional Performance

“…On the one hand, the use of Ti with controlled porosity was proposed as the optimal option to reduce implant stiffness, to make it closer to the natural bone one, and therefore to reduce the stress-shielding phenomenon, one of the main causes of mechanical failure of implants. , However, the introduction of pores into the substrates must be adequate to obtain not only the required biomechanical balance but also good biofunctional behavior, enhancing the vascularization of the implant and bone in-growth and improving the infiltration and adhesion of coatings. On the other hand, the second strategy was focused on the improvement of other characteristics related to implant loosening such as bacterial proliferation or poor osseointegration. , By coating the implant, including the pores, the mechanical, corrosion, and bactericidal behavior are potentially improved, as preferential sites for crack nucleation, attack, and bacterial proliferation are avoided. In addition, much evidence has been reported on the release of Ti particles from Ti implants depending on a wide range of factors such as pH, temperature, dietary and bacterial populations .…”

Recent Progress on the Applications of Nanomaterials and Nano-Characterization Techniques in Endodontics: A Review

“…The impact of the development of novel NPs, their surface modifications, enhanced biofunctional and tribomechanical behaviors, clinical performances, along with various nano-characterization methodologies in the dental field involving endodontics has been emphasized in a number of recent contributions as well [ 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 ]. Studies have shown that the impact of nanomaterials for the treatment of various oral diseases in endodontics is showing fast progress.…”

Preventing Peri-implantitis: The Quest for a Next Generation of Titanium Dental Implants

“…Recently, matrices of silver nanoparticles/polycaprolactone/poly(vinyl alcohol) were used as composite coatings on porous titanium substrates to achieve long-term antibacterial behavior after 21 days. 207 Antimicrobial peptides (AMPs) loaded titania nanotubes have shown release of AMPs for at least 60 days, and demonstrated antibacterial activity against adhered S. aureus for up to 49 days. 208 There are few emerging trends for continuous release of antimicrobial agents, 197 some of which have not been practically tested against oral pathogens on titanium surfaces for peri-implantitis applications.…”

“…Despite the high antimicrobial activity, the study also showed adverse effect of AgNP loaded titania nanotubes as these NPs caused host cell death. Recently, matrices of silver nanoparticles/polycaprolactone/poly­(vinyl alcohol) were used as composite coatings on porous titanium substrates to achieve long-term antibacterial behavior after 21 days . Antimicrobial peptides (AMPs) loaded titania nanotubes have shown release of AMPs for at least 60 days, and demonstrated antibacterial activity against adhered S.…”