Droxidopa has orphan status for the treatment of orthostatic hypotension and is currently not approved for this use in the United States. Currently, donepezil is not FDA approved for treatment of dementia in patients with Parkinson's disease. While fludrocortisone has been used to treat orthostatic hypotension, it does not have FDA approval. Selegiline does have FDA approval for use as an adjunct to levodopa treatment; however, it is not approved for monotherapy to treat Parkinson's disease. Additionally, tamsulosin and terazosin are approved for the treatment of benign prostatic hyperplasia but have been used to treat urinary dysfunction, which is a symptom of prostatic hyperplasia.
AcknowledgementsThe authors acknowledge Chris R. Prostko, PhD, and Joanne M. Faysal, BS, from PRIME ® (Tamarac, Florida) for their assistance with the development and revision of this supplement. Alexandria, VA 22314; 703.683.8416; 703.683.8417 (fax
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Funding and Original Presentation of This Learning ActivityThis supplement was sponsored by PRIME ® through an independent educational grant from Teva Neuroscience. This supplement is based on the proceedings of a satellite symposium held October 15, 2008, at the Kansas City Convention Center in Kansas City, Missouri, in conjunction with the Academy of Managed Care Pharmacy's 2008 Educational Conference, which was supported by an independent grant from Teva Neuroscience.
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