Development of receptor-modified organic transistor-based biosensing

Abstract

With the development of materials and solution-process techniques, organic electronics get increasing attention in bioelectronics. Organic transistors have been considered to be promising candidates for biosensors owing to the functions of signal conversion and amplification, as well as the low operation voltage and long-term stability. In order to realize high sensitivity and selectivity, it is necessary to carry out receptor grafting and surface functionalization, which can facilitate the specific interaction and reduce signal noise. Herein, we summarize recent developments of receptor-functionalized organic transistor-based sensors for smart applications. We first review the fundamentals from the viewpoint of receptor categories, grafting methods and sensing mechanism. Second, we describe the strategies used for receptor assembly and device fabrication. Furthermore, remaining challenges and perspectives are discussed to offer a comprehensive overview of the next generation of corresponding biosensors.

具有触觉感知功能的有机晶体管研究进展

“…内的载流子浓度实现电子开关功能, 是构建逻辑与驱 动电路的基础 [15] . 随着绝缘层材料的开发与器件工作 物理机制认识的深入, 以液相和固相电解质为绝缘层 的电解质绝缘层晶体管(EGOFET)和有机电化学晶体 管(OECT)取得了快速发展 [16,17] . 前者利用栅压在绝缘…”